Seidah NG - Search Results

1

Variation in Serum PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9), Cardiovascular Disease Risk, and an Investigation of Potential Unanticipated Effects of PCSK9 Inhibition.

Brumpton BM, Fritsche LG, Zheng J, Nielsen JB, Mannila M, Surakka I, Rasheed H, Vie GÅ, Graham SE, Gabrielsen ME, Laugsand LE, Aukrust P, Vatten LJ, Damås JK, Ueland T, Janszky I, Zwart JA, Van't Hooft FM, Seidah NG, Hveem K, Willer C, Smith GD, Åsvold BO; INVENT Consortium. Brumpton BM, et al. Among authors: seidah ng. Circ Genom Precis Med. 2019 Jan;12(1):e002335. doi: 10.1161/CIRCGEN.118.002335. Circ Genom Precis Med. 2019. PMID: 30645169 Free PMC article. No abstract available.

2

Implication of the proprotein convertase NARC-1/PCSK9 in the development of the nervous system.

Poirier S, Prat A, Marcinkiewicz E, Paquin J, Chitramuthu BP, Baranowski D, Cadieux B, Bennett HP, Seidah NG. Poirier S, et al. Among authors: seidah ng. J Neurochem. 2006 Aug;98(3):838-50. doi: 10.1111/j.1471-4159.2006.03928.x. J Neurochem. 2006. PMID: 16893422 Free article.

3

Proprotein convertase subtilisin/kexin type 9 (PCSK9): hepatocyte-specific low-density lipoprotein receptor degradation and critical role in mouse liver regeneration.

Zaid A, Roubtsova A, Essalmani R, Marcinkiewicz J, Chamberland A, Hamelin J, Tremblay M, Jacques H, Jin W, Davignon J, Seidah NG, Prat A. Zaid A, et al. Among authors: seidah ng. Hepatology. 2008 Aug;48(2):646-54. doi: 10.1002/hep.22354. Hepatology. 2008. PMID: 18666258

4

Genetic variation at the proprotein convertase subtilisin/kexin type 5 gene modulates high-density lipoprotein cholesterol levels.

Iatan I, Dastani Z, Do R, Weissglas-Volkov D, Ruel I, Lee JC, Huertas-Vazquez A, Taskinen MR, Prat A, Seidah NG, Pajukanta P, Engert JC, Genest J. Iatan I, et al. Among authors: seidah ng. Circ Cardiovasc Genet. 2009 Oct;2(5):467-75. doi: 10.1161/CIRCGENETICS.109.877811. Epub 2009 Aug 22. Circ Cardiovasc Genet. 2009. PMID: 20031622 Free PMC article.

5

Circulating proprotein convertase subtilisin/kexin 9 (PCSK9) regulates VLDLR protein and triglyceride accumulation in visceral adipose tissue.

Roubtsova A, Munkonda MN, Awan Z, Marcinkiewicz J, Chamberland A, Lazure C, Cianflone K, Seidah NG, Prat A. Roubtsova A, et al. Among authors: seidah ng. Arterioscler Thromb Vasc Biol. 2011 Apr;31(4):785-91. doi: 10.1161/ATVBAHA.110.220988. Epub 2011 Jan 27. Arterioscler Thromb Vasc Biol. 2011. PMID: 21273557

6

Gene inactivation of proprotein convertase subtilisin/kexin type 9 reduces atherosclerosis in mice.

Denis M, Marcinkiewicz J, Zaid A, Gauthier D, Poirier S, Lazure C, Seidah NG, Prat A. Denis M, et al. Among authors: seidah ng. Circulation. 2012 Feb 21;125(7):894-901. doi: 10.1161/CIRCULATIONAHA.111.057406. Epub 2012 Jan 18. Circulation. 2012. PMID: 22261195

7

Proprotein convertase subtilisin/kexin type 9 deficiency reduces melanoma metastasis in liver.

Sun X, Essalmani R, Day R, Khatib AM, Seidah NG, Prat A. Sun X, et al. Among authors: seidah ng. Neoplasia. 2012 Dec;14(12):1122-31. doi: 10.1593/neo.121252. Neoplasia. 2012. PMID: 23308045 Free PMC article.

8

Proprotein convertase subtilisin kexin 9 (PCSK9) inhibitors in the treatment of hypercholesterolemia and other pathologies.

Seidah NG. Seidah NG. Curr Pharm Des. 2013;19(17):3161-72. doi: 10.2174/13816128113199990313. Curr Pharm Des. 2013. PMID: 23317404 Review.

9

Proprotein convertase subtilisin/kexin type 9 (PCSK9) can mediate degradation of the low density lipoprotein receptor-related protein 1 (LRP-1).

Canuel M, Sun X, Asselin MC, Paramithiotis E, Prat A, Seidah NG. Canuel M, et al. Among authors: seidah ng. PLoS One. 2013 May 13;8(5):e64145. doi: 10.1371/journal.pone.0064145. Print 2013. PLoS One. 2013. PMID: 23675525 Free PMC article.

10

PCSK9: a key modulator of cardiovascular health.

Seidah NG, Awan Z, Chrétien M, Mbikay M. Seidah NG, et al. Circ Res. 2014 Mar 14;114(6):1022-36. doi: 10.1161/CIRCRESAHA.114.301621. Circ Res. 2014. PMID: 24625727 Review.

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