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Loss of Nmp4 optimizes osteogenic metabolism and secretion to enhance bone quality.
Shao Y, Wichern E, Childress PJ, Adaway M, Misra J, Klunk A, Burr DB, Wek RC, Mosley AL, Liu Y, Robling AG, Brustovetsky N, Hamilton J, Jacobs K, Vashishth D, Stayrook KR, Allen MR, Wallace JM, Bidwell JP. Shao Y, et al. Among authors: liu y. Am J Physiol Endocrinol Metab. 2019 May 1;316(5):E749-E772. doi: 10.1152/ajpendo.00343.2018. Epub 2019 Jan 15. Am J Physiol Endocrinol Metab. 2019. PMID: 30645175 Free PMC article.
Genome-Wide Mapping and Interrogation of the Nmp4 Antianabolic Bone Axis.
Childress P, Stayrook KR, Alvarez MB, Wang Z, Shao Y, Hernandez-Buquer S, Mack JK, Grese ZR, He Y, Horan D, Pavalko FM, Warden SJ, Robling AG, Yang FC, Allen MR, Krishnan V, Liu Y, Bidwell JP. Childress P, et al. Among authors: liu y. Mol Endocrinol. 2015 Sep;29(9):1269-85. doi: 10.1210/me.2014-1406. Epub 2015 Aug 5. Mol Endocrinol. 2015. PMID: 26244796 Free PMC article.
Hypusine biosynthesis in β cells links polyamine metabolism to facultative cellular proliferation to maintain glucose homeostasis.
Levasseur EM, Yamada K, Piñeros AR, Wu W, Syed F, Orr KS, Anderson-Baucum E, Mastracci TL, Maier B, Mosley AL, Liu Y, Bernal-Mizrachi E, Alonso LC, Scott D, Garcia-Ocaña A, Tersey SA, Mirmira RG. Levasseur EM, et al. Among authors: liu y. Sci Signal. 2019 Dec 3;12(610):eaax0715. doi: 10.1126/scisignal.aax0715. Sci Signal. 2019. PMID: 31796630 Free PMC article.
RNA Polymerase II CTD phosphatase Rtr1 fine-tunes transcription termination.
Victorino JF, Fox MJ, Smith-Kinnaman WR, Peck Justice SA, Burriss KH, Boyd AK, Zimmerly MA, Chan RR, Hunter GO, Liu Y, Mosley AL. Victorino JF, et al. Among authors: liu y. PLoS Genet. 2020 Mar 18;16(3):e1008317. doi: 10.1371/journal.pgen.1008317. eCollection 2020 Mar. PLoS Genet. 2020. PMID: 32187185 Free PMC article.
Tumor collection/processing under physioxia uncovers highly relevant signaling networks and drug sensitivity.
Kumar B, Adebayo AK, Prasad M, Capitano ML, Wang R, Bhat-Nakshatri P, Anjanappa M, Simpson E, Chen D, Liu Y, Schilder JM, Colter AB, Maguire C, Temm CJ, Sandusky G, Doud EH, Wijeratne AB, Mosley AL, Broxmeyer HE, Nakshatri H. Kumar B, et al. Among authors: liu y. Sci Adv. 2022 Jan 14;8(2):eabh3375. doi: 10.1126/sciadv.abh3375. Epub 2022 Jan 12. Sci Adv. 2022. PMID: 35020422 Free PMC article.
Single cell cortical bone transcriptomics define novel osteolineage gene sets altered in chronic kidney disease.
Agoro R, Nookaew I, Noonan ML, Marambio YG, Liu S, Chang W, Gao H, Hibbard LM, Metzger CE, Horan D, Thompson WR, Xuei X, Liu Y, Zhang C, Robling AG, Bonewald LF, Wan J, White KE. Agoro R, et al. Among authors: liu y, liu s. Front Endocrinol (Lausanne). 2023 Jan 26;14:1063083. doi: 10.3389/fendo.2023.1063083. eCollection 2023. Front Endocrinol (Lausanne). 2023. PMID: 36777346 Free PMC article.
Loss of succinyl-CoA synthetase in mouse forebrain results in hypersuccinylation with perturbed neuronal transcription and metabolism.
Lancaster MS, Kim B, Doud EH, Tate MD, Sharify AD, Gao H, Chen D, Simpson E, Gillespie P, Chu X, Miller MJ, Wang Y, Liu Y, Mosley AL, Kim J, Graham BH. Lancaster MS, et al. Among authors: liu y. Cell Rep. 2023 Oct 31;42(10):113241. doi: 10.1016/j.celrep.2023.113241. Epub 2023 Oct 17. Cell Rep. 2023. PMID: 37819759 Free PMC article.
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