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Loss of Nmp4 optimizes osteogenic metabolism and secretion to enhance bone quality.
Shao Y, Wichern E, Childress PJ, Adaway M, Misra J, Klunk A, Burr DB, Wek RC, Mosley AL, Liu Y, Robling AG, Brustovetsky N, Hamilton J, Jacobs K, Vashishth D, Stayrook KR, Allen MR, Wallace JM, Bidwell JP. Shao Y, et al. Among authors: stayrook kr. Am J Physiol Endocrinol Metab. 2019 May 1;316(5):E749-E772. doi: 10.1152/ajpendo.00343.2018. Epub 2019 Jan 15. Am J Physiol Endocrinol Metab. 2019. PMID: 30645175 Free PMC article.
Genome-Wide Mapping and Interrogation of the Nmp4 Antianabolic Bone Axis.
Childress P, Stayrook KR, Alvarez MB, Wang Z, Shao Y, Hernandez-Buquer S, Mack JK, Grese ZR, He Y, Horan D, Pavalko FM, Warden SJ, Robling AG, Yang FC, Allen MR, Krishnan V, Liu Y, Bidwell JP. Childress P, et al. Among authors: stayrook kr. Mol Endocrinol. 2015 Sep;29(9):1269-85. doi: 10.1210/me.2014-1406. Epub 2015 Aug 5. Mol Endocrinol. 2015. PMID: 26244796 Free PMC article.
Iron deficiency drives an autosomal dominant hypophosphatemic rickets (ADHR) phenotype in fibroblast growth factor-23 (Fgf23) knock-in mice.
Farrow EG, Yu X, Summers LJ, Davis SI, Fleet JC, Allen MR, Robling AG, Stayrook KR, Jideonwo V, Magers MJ, Garringer HJ, Vidal R, Chan RJ, Goodwin CB, Hui SL, Peacock M, White KE. Farrow EG, et al. Among authors: stayrook kr. Proc Natl Acad Sci U S A. 2011 Nov 15;108(46):E1146-55. doi: 10.1073/pnas.1110905108. Epub 2011 Oct 17. Proc Natl Acad Sci U S A. 2011. PMID: 22006328 Free PMC article.
Regulation of carbohydrate metabolism by the farnesoid X receptor.
Stayrook KR, Bramlett KS, Savkur RS, Ficorilli J, Cook T, Christe ME, Michael LF, Burris TP. Stayrook KR, et al. Endocrinology. 2005 Mar;146(3):984-91. doi: 10.1210/en.2004-0965. Epub 2004 Nov 24. Endocrinology. 2005. PMID: 15564327
Erythropoietin stimulates murine and human fibroblast growth factor-23, revealing novel roles for bone and bone marrow.
Clinkenbeard EL, Hanudel MR, Stayrook KR, Appaiah HN, Farrow EG, Cass TA, Summers LJ, Ip CS, Hum JM, Thomas JC, Ivan M, Richine BM, Chan RJ, Clemens TL, Schipani E, Sabbagh Y, Xu L, Srour EF, Alvarez MB, Kacena MA, Salusky IB, Ganz T, Nemeth E, White KE. Clinkenbeard EL, et al. Among authors: stayrook kr. Haematologica. 2017 Nov;102(11):e427-e430. doi: 10.3324/haematol.2017.167882. Epub 2017 Aug 17. Haematologica. 2017. PMID: 28818868 Free PMC article. No abstract available.
The hypolipidemic natural product guggulsterone is a promiscuous steroid receptor ligand.
Burris TP, Montrose C, Houck KA, Osborne HE, Bocchinfuso WP, Yaden BC, Cheng CC, Zink RW, Barr RJ, Hepler CD, Krishnan V, Bullock HA, Burris LL, Galvin RJ, Bramlett K, Stayrook KR. Burris TP, et al. Among authors: stayrook kr. Mol Pharmacol. 2005 Mar;67(3):948-54. doi: 10.1124/mol.104.007054. Epub 2004 Dec 15. Mol Pharmacol. 2005. PMID: 15602004
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