Ovaa H - Search Results

1

Kinetic analysis of multistep USP7 mechanism shows critical role for target protein in activity.

Kim RQ, Geurink PP, Mulder MPC, Fish A, Ekkebus R, El Oualid F, van Dijk WJ, van Dalen D, Ovaa H, van Ingen H, Sixma TK. Kim RQ, et al. Among authors: ovaa h. Nat Commun. 2019 Jan 16;10(1):231. doi: 10.1038/s41467-018-08231-5. Nat Commun. 2019. PMID: 30651545 Free PMC article.

2

Nonhydrolyzable ubiquitin-isopeptide isosteres as deubiquitinating enzyme probes.

Shanmugham A, Fish A, Luna-Vargas MP, Faesen AC, El Oualid F, Sixma TK, Ovaa H. Shanmugham A, et al. Among authors: ovaa h. J Am Chem Soc. 2010 Jul 7;132(26):8834-5. doi: 10.1021/ja101803s. J Am Chem Soc. 2010. PMID: 20540574

3

Technologies for MHC class I immunoproteomics.

Hoppes R, Ekkebus R, Schumacher TN, Ovaa H. Hoppes R, et al. Among authors: ovaa h. J Proteomics. 2010 Sep 10;73(10):1945-53. doi: 10.1016/j.jprot.2010.05.009. Epub 2010 Jun 8. J Proteomics. 2010. PMID: 20546957 Review.

4

Chemical synthesis of ubiquitin, ubiquitin-based probes, and diubiquitin.

El Oualid F, Merkx R, Ekkebus R, Hameed DS, Smit JJ, de Jong A, Hilkmann H, Sixma TK, Ovaa H. El Oualid F, et al. Among authors: ovaa h. Angew Chem Int Ed Engl. 2010 Dec 27;49(52):10149-53. doi: 10.1002/anie.201005995. Angew Chem Int Ed Engl. 2010. PMID: 21117055 Free PMC article. No abstract available.

5

Structural basis of substrate discrimination and integrin binding by autotaxin.

Hausmann J, Kamtekar S, Christodoulou E, Day JE, Wu T, Fulkerson Z, Albers HM, van Meeteren LA, Houben AJ, van Zeijl L, Jansen S, Andries M, Hall T, Pegg LE, Benson TE, Kasiem M, Harlos K, Kooi CW, Smyth SS, Ovaa H, Bollen M, Morris AJ, Moolenaar WH, Perrakis A. Hausmann J, et al. Among authors: ovaa h. Nat Struct Mol Biol. 2011 Feb;18(2):198-204. doi: 10.1038/nsmb.1980. Epub 2011 Jan 16. Nat Struct Mol Biol. 2011. PMID: 21240271 Free PMC article.

6

Mechanism of USP7/HAUSP activation by its C-terminal ubiquitin-like domain and allosteric regulation by GMP-synthetase.

Faesen AC, Dirac AM, Shanmugham A, Ovaa H, Perrakis A, Sixma TK. Faesen AC, et al. Among authors: ovaa h. Mol Cell. 2011 Oct 7;44(1):147-59. doi: 10.1016/j.molcel.2011.06.034. Mol Cell. 2011. PMID: 21981925 Free article.

7

An ankyrin-repeat ubiquitin-binding domain determines TRABID's specificity for atypical ubiquitin chains.

Licchesi JD, Mieszczanek J, Mevissen TE, Rutherford TJ, Akutsu M, Virdee S, El Oualid F, Chin JW, Ovaa H, Bienz M, Komander D. Licchesi JD, et al. Among authors: ovaa h. Nat Struct Mol Biol. 2011 Dec 11;19(1):62-71. doi: 10.1038/nsmb.2169. Nat Struct Mol Biol. 2011. PMID: 22157957 Free PMC article.

8

The differential modulation of USP activity by internal regulatory domains, interactors and eight ubiquitin chain types.

Faesen AC, Luna-Vargas MP, Geurink PP, Clerici M, Merkx R, van Dijk WJ, Hameed DS, El Oualid F, Ovaa H, Sixma TK. Faesen AC, et al. Among authors: ovaa h. Chem Biol. 2011 Dec 23;18(12):1550-61. doi: 10.1016/j.chembiol.2011.10.017. Chem Biol. 2011. PMID: 22195557

9

A general chemical ligation approach towards isopeptide-linked ubiquitin and ubiquitin-like assay reagents.

Geurink PP, El Oualid F, Jonker A, Hameed DS, Ovaa H. Geurink PP, et al. Among authors: ovaa h. Chembiochem. 2012 Jan 23;13(2):293-7. doi: 10.1002/cbic.201100706. Epub 2011 Dec 23. Chembiochem. 2012. PMID: 22213387 Free PMC article. No abstract available.

10

Synthesis and evaluation of a selective fluorogenic Pup derived assay reagent for Dop, a potential drug target in Mycobacterium tuberculosis.

Merkx R, Burns KE, Slobbe P, El Oualid F, El Atmioui D, Darwin KH, Ovaa H. Merkx R, et al. Among authors: ovaa h. Chembiochem. 2012 Sep 24;13(14):2056-60. doi: 10.1002/cbic.201200460. Epub 2012 Aug 24. Chembiochem. 2012. PMID: 22927162 Free PMC article.

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