Howe MD - Search Results

1

Investigation of ( S)-(-)-Acidomycin: A Selective Antimycobacterial Natural Product That Inhibits Biotin Synthase.

Bockman MR, Engelhart CA, Cramer JD, Howe MD, Mishra NK, Zimmerman M, Larson P, Alvarez-Cabrera N, Park SW, Boshoff HIM, Bean JM, Young VG Jr, Ferguson DM, Dartois V, Jarrett JT, Schnappinger D, Aldrich CC. Bockman MR, et al. Among authors: howe md. ACS Infect Dis. 2019 Apr 12;5(4):598-617. doi: 10.1021/acsinfecdis.8b00345. Epub 2019 Feb 4. ACS Infect Dis. 2019. PMID: 30652474 Free PMC article.

2

Spirocyclic and Bicyclic 8-Nitrobenzothiazinones for Tuberculosis with Improved Physicochemical and Pharmacokinetic Properties.

Zhang G, Howe M, Aldrich CC. Zhang G, et al. ACS Med Chem Lett. 2019 Feb 23;10(3):348-351. doi: 10.1021/acsmedchemlett.8b00634. eCollection 2019 Mar 14. ACS Med Chem Lett. 2019. PMID: 30891138 Free PMC article.

3

Methionine Antagonizes para-Aminosalicylic Acid Activity via Affecting Folate Precursor Biosynthesis in Mycobacterium tuberculosis.

Howe MD, Kordus SL, Cole MS, Bauman AA, Aldrich CC, Baughn AD, Minato Y. Howe MD, et al. Front Cell Infect Microbiol. 2018 Nov 12;8:399. doi: 10.3389/fcimb.2018.00399. eCollection 2018. Front Cell Infect Microbiol. 2018. PMID: 30483484 Free PMC article.

4

Synthesis and biological evaluation of orally active prodrugs and analogs of para-aminosalicylic acid (PAS).

Hegde PV, Howe MD, Zimmerman MD, Boshoff HIM, Sharma S, Remache B, Jia Z, Pan Y, Baughn AD, Dartois V, Aldrich CC. Hegde PV, et al. Among authors: howe md. Eur J Med Chem. 2022 Mar 15;232:114201. doi: 10.1016/j.ejmech.2022.114201. Epub 2022 Feb 19. Eur J Med Chem. 2022. PMID: 35219151 Free PMC article.

5

Cephem-Pyrazinoic Acid Conjugates: Circumventing Resistance in Mycobacterium tuberculosis.

Cole MS, Howe MD, Buonomo JA, Sharma S, Lamont EA, Brody SI, Mishra NK, Minato Y, Thiede JM, Baughn AD, Aldrich CC. Cole MS, et al. Among authors: howe md. Chemistry. 2022 Sep 12;28(51):e202200995. doi: 10.1002/chem.202200995. Epub 2022 Jul 27. Chemistry. 2022. PMID: 35697660 Free PMC article.

6

Pathogen-specific antimicrobials engineered de novo through membrane-protein biomimicry.

Simonson AW, Mongia AS, Aronson MR, Alumasa JN, Chan DC, Lawanprasert A, Howe MD, Bolotsky A, Mal TK, George C, Ebrahimi A, Baughn AD, Proctor EA, Keiler KC, Medina SH. Simonson AW, et al. Among authors: howe md. Nat Biomed Eng. 2021 May;5(5):467-480. doi: 10.1038/s41551-020-00665-x. Epub 2021 Jan 4. Nat Biomed Eng. 2021. PMID: 33390588 Free PMC article.

7

Pyrazinamide Susceptibility Is Driven by Activation of the SigE-Dependent Cell Envelope Stress Response in Mycobacterium tuberculosis.

Thiede JM, Dillon NA, Howe MD, Aflakpui R, Modlin SJ, Hoffner SE, Valafar F, Minato Y, Baughn AD. Thiede JM, et al. Among authors: howe md. mBio. 2021 Feb 22;13(1):e0043921. doi: 10.1128/mbio.00439-21. Epub 2022 Feb 1. mBio. 2021. PMID: 35100871 Free PMC article.

8

Wearable bluetooth sensors for capturing relational variables and temporal variability in relationships: A construct validation study.

Matusik JG, Heidl R, Hollenbeck JR, Yu A, Lee HW, Howe M. Matusik JG, et al. J Appl Psychol. 2019 Mar;104(3):357-387. doi: 10.1037/apl0000334. Epub 2018 Aug 2. J Appl Psychol. 2019. PMID: 30070543

9

When discretionary boundary spanning relationships cease becoming discretionary: The impact of closed ties on informal leadership perceptions.

Guo ZA, Heidl RA, Hollenbeck JR, Yu A, Howe M. Guo ZA, et al. J Appl Psychol. 2022 Jun;107(6):898-916. doi: 10.1037/apl0000911. Epub 2021 Dec 23. J Appl Psychol. 2022. PMID: 34941291

10

Small sample mediation testing: misplaced confidence in bootstrapped confidence intervals.

Koopman J, Howe M, Hollenbeck JR, Sin HP. Koopman J, et al. J Appl Psychol. 2015 Jan;100(1):194-202. doi: 10.1037/a0036635. Epub 2014 Apr 14. J Appl Psychol. 2015. PMID: 24731180

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