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The cholesterol biosynthesis pathway regulates IL-10 expression in human Th1 cells.
Perucha E, Melchiotti R, Bibby JA, Wu W, Frederiksen KS, Roberts CA, Hall Z, LeFriec G, Robertson KA, Lavender P, Gerwien JG, Taams LS, Griffin JL, de Rinaldis E, van Baarsen LGM, Kemper C, Ghazal P, Cope AP. Perucha E, et al. Among authors: taams ls. Nat Commun. 2019 Jan 30;10(1):498. doi: 10.1038/s41467-019-08332-9. Nat Commun. 2019. PMID: 30700717 Free PMC article.
CD161 expression characterizes a subpopulation of human regulatory T cells that produces IL-17 in a STAT3-dependent manner.
Afzali B, Mitchell PJ, Edozie FC, Povoleri GA, Dowson SE, Demandt L, Walter G, Canavan JB, Scotta C, Menon B, Chana PS, Khamri W, Kordasti SY, Heck S, Grimbacher B, Tree T, Cope AP, Taams LS, Lechler RI, John S, Lombardi G. Afzali B, et al. Among authors: taams ls. Eur J Immunol. 2013 Aug;43(8):2043-54. doi: 10.1002/eji.201243296. Epub 2013 Jul 3. Eur J Immunol. 2013. PMID: 23677517 Free PMC article.
TNF-α blockade induces IL-10 expression in human CD4+ T cells.
Evans HG, Roostalu U, Walter GJ, Gullick NJ, Frederiksen KS, Roberts CA, Sumner J, Baeten DL, Gerwien JG, Cope AP, Geissmann F, Kirkham BW, Taams LS. Evans HG, et al. Among authors: taams ls. Nat Commun. 2014;5:3199. doi: 10.1038/ncomms4199. Nat Commun. 2014. PMID: 24492460 Free PMC article.
IL-17 in the immunopathogenesis of spondyloarthritis.
Taams LS, Steel KJA, Srenathan U, Burns LA, Kirkham BW. Taams LS, et al. Nat Rev Rheumatol. 2018 Aug;14(8):453-466. doi: 10.1038/s41584-018-0044-2. Nat Rev Rheumatol. 2018. PMID: 30006601 Review.
Anti-TNF treatment negatively regulates human CD4+ T-cell activation and maturation in vitro, but does not confer an anergic or suppressive phenotype.
Povoleri GAM, Lalnunhlimi S, Steel KJA, Agrawal S, O'Byrne AM, Ridley M, Kordasti S, Frederiksen KS, Roberts CA, Taams LS. Povoleri GAM, et al. Among authors: taams ls. Eur J Immunol. 2020 Mar;50(3):445-458. doi: 10.1002/eji.201948190. Epub 2019 Dec 3. Eur J Immunol. 2020. PMID: 31722123 Free PMC article.
100 results