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CCL27/CCL28-CCR10 Chemokine Signaling Mediates Migration of Lymphatic Endothelial Cells.
Karnezis T, Farnsworth RH, Harris NC, Williams SP, Caesar C, Byrne DJ, Herle P, Macheda ML, Shayan R, Zhang YF, Yazar S, Takouridis SJ, Gerard C, Fox SB, Achen MG, Stacker SA. Karnezis T, et al. Among authors: williams sp. Cancer Res. 2019 Apr 1;79(7):1558-1572. doi: 10.1158/0008-5472.CAN-18-1858. Epub 2019 Feb 1. Cancer Res. 2019. PMID: 30709930
A system for quantifying the patterning of the lymphatic vasculature.
Shayan R, Karnezis T, Tsantikos E, Williams SP, Runting AS, Ashton MW, Achen MG, Hibbs ML, Stacker SA. Shayan R, et al. Among authors: williams sp. Growth Factors. 2007 Dec;25(6):417-25. doi: 10.1080/08977190801932550. Growth Factors. 2007. PMID: 18365872
VEGF-D promotes tumor metastasis by regulating prostaglandins produced by the collecting lymphatic endothelium.
Karnezis T, Shayan R, Caesar C, Roufail S, Harris NC, Ardipradja K, Zhang YF, Williams SP, Farnsworth RH, Chai MG, Rupasinghe TW, Tull DL, Baldwin ME, Sloan EK, Fox SB, Achen MG, Stacker SA. Karnezis T, et al. Among authors: williams sp. Cancer Cell. 2012 Feb 14;21(2):181-95. doi: 10.1016/j.ccr.2011.12.026. Cancer Cell. 2012. PMID: 22340592 Free article.
Lymphangiogenesis and lymphatic vessel remodelling in cancer.
Stacker SA, Williams SP, Karnezis T, Shayan R, Fox SB, Achen MG. Stacker SA, et al. Among authors: williams sp. Nat Rev Cancer. 2014 Mar;14(3):159-72. doi: 10.1038/nrc3677. Nat Rev Cancer. 2014. PMID: 24561443 Review.
Differential Receptor Binding and Regulatory Mechanisms for the Lymphangiogenic Growth Factors Vascular Endothelial Growth Factor (VEGF)-C and -D.
Davydova N, Harris NC, Roufail S, Paquet-Fifield S, Ishaq M, Streltsov VA, Williams SP, Karnezis T, Stacker SA, Achen MG. Davydova N, et al. Among authors: williams sp. J Biol Chem. 2016 Dec 30;291(53):27265-27278. doi: 10.1074/jbc.M116.736801. Epub 2016 Nov 16. J Biol Chem. 2016. PMID: 27852824 Free PMC article.
Genome-wide functional analysis reveals central signaling regulators of lymphatic endothelial cell migration and remodeling.
Williams SP, Odell AF, Karnezis T, Farnsworth RH, Gould CM, Li J, Paquet-Fifield S, Harris NC, Walter A, Gregory JL, Lamont SF, Liu R, Takano EA, Nowell CJ, Bower NI, Resnick D, Smyth GK, Coultas L, Hogan BM, Fox SB, Mueller SN, Simpson KJ, Achen MG, Stacker SA. Williams SP, et al. Sci Signal. 2017 Oct 3;10(499):eaal2987. doi: 10.1126/scisignal.aal2987. Sci Signal. 2017. PMID: 28974649
Genome-wide chemical mutagenesis screens allow unbiased saturation of the cancer genome and identification of drug resistance mutations.
Brammeld JS, Petljak M, Martincorena I, Williams SP, Alonso LG, Dalmases A, Bellosillo B, Robles-Espinoza CD, Price S, Barthorpe S, Tarpey P, Alifrangis C, Bignell G, Vidal J, Young J, Stebbings L, Beal K, Stratton MR, Saez-Rodriguez J, Garnett M, Montagut C, Iorio F, McDermott U. Brammeld JS, et al. Among authors: williams sp. Genome Res. 2017 Apr;27(4):613-625. doi: 10.1101/gr.213546.116. Epub 2017 Feb 8. Genome Res. 2017. PMID: 28179366 Free PMC article.
258 results