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APOE4-mediated amyloid-β pathology depends on its neuronal receptor LRP1.
Tachibana M, Holm ML, Liu CC, Shinohara M, Aikawa T, Oue H, Yamazaki Y, Martens YA, Murray ME, Sullivan PM, Weyer K, Glerup S, Dickson DW, Bu G, Kanekiyo T. Tachibana M, et al. Among authors: yamazaki y. J Clin Invest. 2019 Mar 1;129(3):1272-1277. doi: 10.1172/JCI124853. Epub 2019 Feb 11. J Clin Invest. 2019. PMID: 30741718 Free PMC article.
Modulation of mitochondrial complex I activity averts cognitive decline in multiple animal models of familial Alzheimer's Disease.
Zhang L, Zhang S, Maezawa I, Trushin S, Minhas P, Pinto M, Jin LW, Prasain K, Nguyen TD, Yamazaki Y, Kanekiyo T, Bu G, Gateno B, Chang KO, Nath KA, Nemutlu E, Dzeja P, Pang YP, Hua DH, Trushina E. Zhang L, et al. Among authors: yamazaki y. EBioMedicine. 2015 Apr 1;2(4):294-305. doi: 10.1016/j.ebiom.2015.03.009. EBioMedicine. 2015. PMID: 26086035 Free PMC article.
ABCA7 Deficiency Accelerates Amyloid-β Generation and Alzheimer's Neuronal Pathology.
Sakae N, Liu CC, Shinohara M, Frisch-Daiello J, Ma L, Yamazaki Y, Tachibana M, Younkin L, Kurti A, Carrasquillo MM, Zou F, Sevlever D, Bisceglio G, Gan M, Fol R, Knight P, Wang M, Han X, Fryer JD, Fitzgerald ML, Ohyagi Y, Younkin SG, Bu G, Kanekiyo T. Sakae N, et al. Among authors: yamazaki y. J Neurosci. 2016 Mar 30;36(13):3848-59. doi: 10.1523/JNEUROSCI.3757-15.2016. J Neurosci. 2016. PMID: 27030769 Free PMC article.
Impact of sex and APOE4 on cerebral amyloid angiopathy in Alzheimer's disease.
Shinohara M, Murray ME, Frank RD, Shinohara M, DeTure M, Yamazaki Y, Tachibana M, Atagi Y, Davis MD, Liu CC, Zhao N, Painter MM, Petersen RC, Fryer JD, Crook JE, Dickson DW, Bu G, Kanekiyo T. Shinohara M, et al. Among authors: yamazaki y. Acta Neuropathol. 2016 Aug;132(2):225-234. doi: 10.1007/s00401-016-1580-y. Epub 2016 May 14. Acta Neuropathol. 2016. PMID: 27179972 Free PMC article.
2,934 results