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A Macrophage-Pericyte Axis Directs Tissue Restoration via Amphiregulin-Induced Transforming Growth Factor Beta Activation.
Minutti CM, Modak RV, Macdonald F, Li F, Smyth DJ, Dorward DA, Blair N, Husovsky C, Muir A, Giampazolias E, Dobie R, Maizels RM, Kendall TJ, Griggs DW, Kopf M, Henderson NC, Zaiss DM. Minutti CM, et al. Among authors: modak rv. Immunity. 2019 Mar 19;50(3):645-654.e6. doi: 10.1016/j.immuni.2019.01.008. Epub 2019 Feb 12. Immunity. 2019. PMID: 30770250 Free PMC article.
Targeting CCL2/CCR2 Signaling Overcomes MEK Inhibitor Resistance in Acute Myeloid Leukemia.
Modak RV, de Oliveira Rebola KG, McClatchy J, Mohammadhosseini M, Damnernsawad A, Kurtz SE, Eide CA, Wu G, Laderas T, Nechiporuk T, Gritsenko MA, Hansen JR, Hutchinson C, Gosline SJC, Piehowski P, Bottomly D, Short N, Rodland K, McWeeney SK, Tyner JW, Agarwal A. Modak RV, et al. Clin Cancer Res. 2024 May 15;30(10):2245-2259. doi: 10.1158/1078-0432.CCR-23-2654. Clin Cancer Res. 2024. PMID: 38451486 Free PMC article.
Imidazolone as an Amide Bioisostere in the Development of β-1,3-N-Acetylglucosaminyltransferase 2 (B3GNT2) Inhibitors.
Jackson JJ, Siegmund AC, Bai WJ, Reed AB, Birkholz AB, Campuzano IDG, Créquer-Grandhomme A, Hu R, Modak RV, Sudom A, Javier N, Sanders C, Lo MC, Xie F, Cee VJ, Manzanillo P, Allen JG. Jackson JJ, et al. Among authors: modak rv. J Med Chem. 2023 Dec 14;66(23):16120-16140. doi: 10.1021/acs.jmedchem.3c01517. Epub 2023 Nov 21. J Med Chem. 2023. PMID: 37988652