Kobayakawa T - Search Results

1

Design, synthesis and biological evaluation of low molecular weight CXCR4 ligands.

Sakyiamah MM, Kobayakawa T, Fujino M, Konno M, Narumi T, Tanaka T, Nomura W, Yamamoto N, Murakami T, Tamamura H. Sakyiamah MM, et al. Among authors: kobayakawa t. Bioorg Med Chem. 2019 Mar 15;27(6):1130-1138. doi: 10.1016/j.bmc.2019.02.013. Epub 2019 Feb 6. Bioorg Med Chem. 2019. PMID: 30772128

2

Stereoselective formation of trisubstituted (Z)-chloroalkenes adjacent to a tertiary carbon stereogenic center by organocuprate-mediated reduction/alkylation.

Narumi T, Kobayakawa T, Aikawa H, Seike S, Tamamura H. Narumi T, et al. Among authors: kobayakawa t. Org Lett. 2012 Sep 7;14(17):4490-3. doi: 10.1021/ol301988d. Epub 2012 Aug 17. Org Lett. 2012. PMID: 22900591

3

Low-molecular-weight CXCR4 ligands with variable spacers.

Narumi T, Aikawa H, Tanaka T, Hashimoto C, Ohashi N, Nomura W, Kobayakawa T, Takano H, Hirota Y, Murakami T, Yamamoto N, Tamamura H. Narumi T, et al. Among authors: kobayakawa t. ChemMedChem. 2013 Jan;8(1):118-24. doi: 10.1002/cmdc.201200390. Epub 2012 Oct 19. ChemMedChem. 2013. PMID: 23086703

4

Remote Stereoinduction in the Organocuprate-Mediated Allylic Alkylation of Allylic gem-Dichlorides: Highly Diastereoselective Synthesis of (Z)-Chloroalkene Dipeptide Isosteres.

Kobayakawa T, Narumi T, Tamamura H. Kobayakawa T, et al. Org Lett. 2015 May 15;17(10):2302-5. doi: 10.1021/acs.orglett.5b00611. Epub 2015 May 7. Org Lett. 2015. PMID: 25950639

5

Synthesis and Evaluation of Dimeric Derivatives of Diacylglycerol-Lactones as Protein Kinase C Ligands.

Ohashi N, Kobayashi R, Nomura W, Kobayakawa T, Czikora A, Herold BK, Lewin NE, Blumberg PM, Tamamura H. Ohashi N, et al. Among authors: kobayakawa t. Bioconjug Chem. 2017 Aug 16;28(8):2135-2144. doi: 10.1021/acs.bioconjchem.7b00299. Epub 2017 Jul 21. Bioconjug Chem. 2017. PMID: 28671468 Free PMC article.

6

Synthesis of a Chloroalkene Dipeptide Isostere-Containing Peptidomimetic and Its Biological Application.

Kobayakawa T, Matsuzaki Y, Hozumi K, Nomura W, Nomizu M, Tamamura H. Kobayakawa T, et al. ACS Med Chem Lett. 2017 Dec 27;9(1):6-10. doi: 10.1021/acsmedchemlett.7b00234. eCollection 2018 Jan 11. ACS Med Chem Lett. 2017. PMID: 29348803 Free PMC article.

7

Delivery of a Proapoptotic Peptide to EGFR-Positive Cancer Cells by a Cyclic Peptide Mimicking the Dimerization Arm Structure of EGFR.

Toyama K, Nomura W, Kobayakawa T, Tamamura H. Toyama K, et al. Among authors: kobayakawa t. Bioconjug Chem. 2018 Jun 20;29(6):2050-2057. doi: 10.1021/acs.bioconjchem.8b00250. Epub 2018 May 31. Bioconjug Chem. 2018. PMID: 29763296

8

Efficient and Orthogonal Transcription Regulation by Chemically Inducible Artificial Transcription Factors.

Nomura W, Matsumoto D, Sugii T, Kobayakawa T, Tamamura H. Nomura W, et al. Among authors: kobayakawa t. Biochemistry. 2018 Nov 13;57(45):6452-6459. doi: 10.1021/acs.biochem.8b00741. Epub 2018 Nov 2. Biochemistry. 2018. PMID: 30366497

9

Flexibility of small molecular CD4 mimics as HIV entry inhibitors.

Kobayakawa T, Ohashi N, Hirota Y, Takahashi K, Yamada Y, Narumi T, Yoshimura K, Matsushita S, Harada S, Tamamura H. Kobayakawa T, et al. Bioorg Med Chem. 2018 Nov 15;26(21):5664-5671. doi: 10.1016/j.bmc.2018.10.011. Epub 2018 Oct 16. Bioorg Med Chem. 2018. PMID: 30366786

10

Inhibition of EGFR Activation by Bivalent Ligands Based on a Cyclic Peptide Mimicking the Dimerization Arm Structure of EGFR.

Toyama K, Kobayakawa T, Nomura W, Tamamura H. Toyama K, et al. Among authors: kobayakawa t. Chem Pharm Bull (Tokyo). 2018;66(11):1083-1089. doi: 10.1248/cpb.c18-00539. Chem Pharm Bull (Tokyo). 2018. PMID: 30381661 Free article.

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