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A Long-Acting PYY3-36 Analog Mediates Robust Anorectic Efficacy with Minimal Emesis in Nonhuman Primates.
Rangwala SM, D'Aquino K, Zhang YM, Bader L, Edwards W, Zheng S, Eckardt A, Lacombe A, Pick R, Moreno V, Kang L, Jian W, Arnoult E, Case M, Jenkinson C, Chi E, Swanson RV, Kievit P, Grove K, Macielag M, Erion MD, SinhaRoy R, Leonard JN. Rangwala SM, et al. Among authors: grove k. Cell Metab. 2019 Apr 2;29(4):837-843.e5. doi: 10.1016/j.cmet.2019.01.017. Epub 2019 Feb 14. Cell Metab. 2019. PMID: 30773465 Free PMC article.
The nonhuman primate as a model for type 2 diabetes.
Pound LD, Kievit P, Grove KL. Pound LD, et al. Curr Opin Endocrinol Diabetes Obes. 2014 Apr;21(2):89-94. doi: 10.1097/MED.0000000000000043. Curr Opin Endocrinol Diabetes Obes. 2014. PMID: 24569549 Review.
Proinflammatory endothelial activation detected by molecular imaging in obese nonhuman primates coincides with onset of insulin resistance and progressively increases with duration of insulin resistance.
Chadderdon SM, Belcik JT, Bader L, Kirigiti MA, Peters DM, Kievit P, Grove KL, Lindner JR. Chadderdon SM, et al. Circulation. 2014 Jan 28;129(4):471-8. doi: 10.1161/CIRCULATIONAHA.113.003645. Epub 2013 Oct 25. Circulation. 2014. PMID: 24163066 Free PMC article.
FGF21 decreases body weight without reducing food intake or bone mineral density in high-fat fed obese rhesus macaque monkeys.
Andersen B, Straarup EM, Heppner KM, Takahashi DL, Raffaele V, Dissen GA, Lewandowski K, Bödvarsdottir TB, Raun K, Grove KL, Kievit P. Andersen B, et al. Among authors: grove kl. Int J Obes (Lond). 2018 Jun;42(6):1151-1160. doi: 10.1038/s41366-018-0080-7. Epub 2018 Jun 11. Int J Obes (Lond). 2018. PMID: 29892039 Free PMC article.
Single-cell analysis of insulin-regulated fatty acid uptake in adipocytes.
Varlamov O, Somwar R, Cornea A, Kievit P, Grove KL, Roberts CT Jr. Varlamov O, et al. Am J Physiol Endocrinol Metab. 2010 Sep;299(3):E486-96. doi: 10.1152/ajpendo.00330.2010. Epub 2010 Jun 22. Am J Physiol Endocrinol Metab. 2010. PMID: 20570821 Free PMC article.
249 results