Clarke P - Search Results

1

An FBXW7-ZEB2 axis links EMT and tumour microenvironment to promote colorectal cancer stem cells and chemoresistance.

Li N, Babaei-Jadidi R, Lorenzi F, Spencer-Dene B, Clarke P, Domingo E, Tulchinsky E, Vries RGJ, Kerr D, Pan Y, He Y, Bates DO, Tomlinson I, Clevers H, Nateri AS. Li N, et al. Among authors: clarke p. Oncogenesis. 2019 Feb 19;8(3):13. doi: 10.1038/s41389-019-0125-3. Oncogenesis. 2019. PMID: 30783098 Free PMC article.

2

Phosphodiesterase type 5 inhibitors enhance chemotherapy in preclinical models of esophageal adenocarcinoma by targeting cancer-associated fibroblasts.

Sharpe BP, Hayden A, Manousopoulou A, Cowie A, Walker RC, Harrington J, Izadi F, Breininger SP, Gibson J, Pickering O, Jaynes E, Kyle E, Saunders JH, Parsons SL, Ritchie AA, Clarke PA, Collier P, Mongan NP, Bates DO, Yacqub-Usman K, Garbis SD, Walters Z, Rose-Zerilli M, Grabowska AM, Underwood TJ. Sharpe BP, et al. Among authors: clarke pa. Cell Rep Med. 2022 Jun 21;3(6):100541. doi: 10.1016/j.xcrm.2022.100541. Cell Rep Med. 2022. PMID: 35732148 Free PMC article.

3

A 3D Heterotypic Breast Cancer Model Demonstrates a Role for Mesenchymal Stem Cells in Driving a Proliferative and Invasive Phenotype.

Pal A, Ashworth JC, Collier P, Probert C, Jones S, Leza EP, Meakin ML, A Ritchie A, Onion D, Clarke PA, Allegrucci C, Grabowska AM. Pal A, et al. Among authors: clarke pa. Cancers (Basel). 2020 Aug 14;12(8):2290. doi: 10.3390/cancers12082290. Cancers (Basel). 2020. PMID: 32824003 Free PMC article.

4

The influence of tumour cell DNA content on survival in colorectal cancer: a detailed analysis.

Armitage NC, Ballantyne KC, Evans DF, Clarke P, Sheffield J, Hardcastle JD. Armitage NC, et al. Among authors: clarke p. Br J Cancer. 1990 Nov;62(5):852-6. doi: 10.1038/bjc.1990.393. Br J Cancer. 1990. PMID: 2245180 Free PMC article.

5

Helicobacter pylori potentiates epithelial:mesenchymal transition in gastric cancer: links to soluble HB-EGF, gastrin and matrix metalloproteinase-7.

Yin Y, Grabowska AM, Clarke PA, Whelband E, Robinson K, Argent RH, Tobias A, Kumari R, Atherton JC, Watson SA. Yin Y, et al. Gut. 2010 Aug;59(8):1037-45. doi: 10.1136/gut.2009.199794. Epub 2010 Jun 28. Gut. 2010. PMID: 20584780 Free PMC article.

6

Individual patient oesophageal cancer 3D models for tailored treatment.

Saunders JH, Onion D, Collier P, Dorrington MS, Argent RH, Clarke PA, Reece-Smith AM, Parsons SL, Grabowska AM. Saunders JH, et al. Among authors: clarke pa. Oncotarget. 2017 Apr 11;8(15):24224-24236. doi: 10.18632/oncotarget.12500. Oncotarget. 2017. PMID: 27736801 Free PMC article.

7

Cancer reversion with oocyte extracts is mediated by cell cycle arrest and induction of tumour dormancy.

Saad N, Alberio R, Johnson AD, Emes RD, Giles TC, Clarke P, Grabowska AM, Allegrucci C. Saad N, et al. Among authors: clarke p. Oncotarget. 2018 Mar 23;9(22):16008-16027. doi: 10.18632/oncotarget.24664. eCollection 2018 Mar 23. Oncotarget. 2018. PMID: 29662623 Free PMC article.

8

Synthesis of micellar-like terpolymer nanoparticles with reductively-cleavable cross-links and evaluation of efficacy in 2D and 3D models of triple negative breast cancer.

Monteiro PF, Gulfam M, Monteiro CJ, Travanut A, Abelha TF, Pearce AK, Jerôme C, Grabowska AM, Clarke PA, Collins HM, Heery DM, Gershkovich P, Alexander C. Monteiro PF, et al. Among authors: clarke pa. J Control Release. 2020 Jul 10;323:549-564. doi: 10.1016/j.jconrel.2020.04.049. Epub 2020 May 3. J Control Release. 2020. PMID: 32371266

9

Metabolism-based isolation of invasive glioblastoma cells with specific gene signatures and tumorigenic potential.

Smith SJ, Rowlinson J, Estevez-Cebrero M, Onion D, Ritchie A, Clarke P, Wood K, Diksin M, Lourdusamy A, Grundy RG, Rahman R. Smith SJ, et al. Among authors: clarke p. Neurooncol Adv. 2020 Jul 13;2(1):vdaa087. doi: 10.1093/noajnl/vdaa087. eCollection 2020 Jan-Dec. Neurooncol Adv. 2020. PMID: 32904996 Free PMC article.

10

Gelatinase (MMP-2 and -9) expression in gastrointestinal malignancy.

Parsons SL, Watson SA, Collins HM, Griffin NR, Clarke PA, Steele RJ. Parsons SL, et al. Among authors: clarke pa. Br J Cancer. 1998 Dec;78(11):1495-502. doi: 10.1038/bjc.1998.712. Br J Cancer. 1998. PMID: 9836483 Free PMC article.

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