Spencer-Dene B - Search Results

1

An FBXW7-ZEB2 axis links EMT and tumour microenvironment to promote colorectal cancer stem cells and chemoresistance.

Li N, Babaei-Jadidi R, Lorenzi F, Spencer-Dene B, Clarke P, Domingo E, Tulchinsky E, Vries RGJ, Kerr D, Pan Y, He Y, Bates DO, Tomlinson I, Clevers H, Nateri AS. Li N, et al. Among authors: spencer dene b. Oncogenesis. 2019 Feb 19;8(3):13. doi: 10.1038/s41389-019-0125-3. Oncogenesis. 2019. PMID: 30783098 Free PMC article.

2

Embryonic NANOG activity defines colorectal cancer stem cells and modulates through AP1- and TCF-dependent mechanisms.

Ibrahim EE, Babaei-Jadidi R, Saadeddin A, Spencer-Dene B, Hossaini S, Abuzinadah M, Li N, Fadhil W, Ilyas M, Bonnet D, Nateri AS. Ibrahim EE, et al. Stem Cells. 2012 Oct;30(10):2076-87. doi: 10.1002/stem.1182. Stem Cells. 2012. PMID: 22851508

3

Fbxw7-associated drug resistance is reversed by induction of terminal differentiation in murine intestinal organoid culture.

Lorenzi F, Babaei-Jadidi R, Sheard J, Spencer-Dene B, Nateri AS. Lorenzi F, et al. Mol Ther Methods Clin Dev. 2016 Apr 13;3:16024. doi: 10.1038/mtm.2016.24. eCollection 2016. Mol Ther Methods Clin Dev. 2016. PMID: 27110583 Free PMC article.

4

The links between transcription, beta-catenin/JNK signaling, and carcinogenesis.

Saadeddin A, Babaei-Jadidi R, Spencer-Dene B, Nateri AS. Saadeddin A, et al. Mol Cancer Res. 2009 Aug;7(8):1189-96. doi: 10.1158/1541-7786.MCR-09-0027. Epub 2009 Aug 11. Mol Cancer Res. 2009. PMID: 19671687 Review.

5

FBXW7 influences murine intestinal homeostasis and cancer, targeting Notch, Jun, and DEK for degradation.

Babaei-Jadidi R, Li N, Saadeddin A, Spencer-Dene B, Jandke A, Muhammad B, Ibrahim EE, Muraleedharan R, Abuzinadah M, Davis H, Lewis A, Watson S, Behrens A, Tomlinson I, Nateri AS. Babaei-Jadidi R, et al. J Exp Med. 2011 Feb 14;208(2):295-312. doi: 10.1084/jem.20100830. Epub 2011 Jan 31. J Exp Med. 2011. PMID: 21282377 Free PMC article.

6

FLYWCH1, a Novel Suppressor of Nuclear β-Catenin, Regulates Migration and Morphology in Colorectal Cancer.

Muhammad BA, Almozyan S, Babaei-Jadidi R, Onyido EK, Saadeddin A, Kashfi SH, Spencer-Dene B, Ilyas M, Lourdusamy A, Behrens A, Nateri AS. Muhammad BA, et al. Among authors: spencer dene b. Mol Cancer Res. 2018 Dec;16(12):1977-1990. doi: 10.1158/1541-7786.MCR-18-0262. Epub 2018 Aug 10. Mol Cancer Res. 2018. PMID: 30097457 Free PMC article.

7

FBXW7 mutations typically found in human cancers are distinct from null alleles and disrupt lung development.

Davis H, Lewis A, Spencer-Dene B, Tateossian H, Stamp G, Behrens A, Tomlinson I. Davis H, et al. J Pathol. 2011 Jun;224(2):180-9. doi: 10.1002/path.2874. Epub 2011 Apr 18. J Pathol. 2011. PMID: 21503901 Free PMC article.

8

Interaction of phosphorylated c-Jun with TCF4 regulates intestinal cancer development.

Nateri AS, Spencer-Dene B, Behrens A. Nateri AS, et al. Nature. 2005 Sep 8;437(7056):281-5. doi: 10.1038/nature03914. Epub 2005 Jul 10. Nature. 2005. PMID: 16007074 Free article.

9

JNK signalling modulates intestinal homeostasis and tumourigenesis in mice.

Sancho R, Nateri AS, de Vinuesa AG, Aguilera C, Nye E, Spencer-Dene B, Behrens A. Sancho R, et al. EMBO J. 2009 Jul 8;28(13):1843-54. doi: 10.1038/emboj.2009.153. Epub 2009 Jun 11. EMBO J. 2009. PMID: 19521338 Free PMC article.

10

BCL9L Dysfunction Impairs Caspase-2 Expression Permitting Aneuploidy Tolerance in Colorectal Cancer.

López-García C, Sansregret L, Domingo E, McGranahan N, Hobor S, Birkbak NJ, Horswell S, Grönroos E, Favero F, Rowan AJ, Matthews N, Begum S, Phillimore B, Burrell R, Oukrif D, Spencer-Dene B, Kovac M, Stamp G, Stewart A, Danielsen H, Novelli M, Tomlinson I, Swanton C. López-García C, et al. Cancer Cell. 2017 Jan 9;31(1):79-93. doi: 10.1016/j.ccell.2016.11.001. Cancer Cell. 2017. PMID: 28073006 Free PMC article.

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