Nichols J - Search Results

1

A single-cell molecular map of mouse gastrulation and early organogenesis.

Pijuan-Sala B, Griffiths JA, Guibentif C, Hiscock TW, Jawaid W, Calero-Nieto FJ, Mulas C, Ibarra-Soria X, Tyser RCV, Ho DLL, Reik W, Srinivas S, Simons BD, Nichols J, Marioni JC, Göttgens B. Pijuan-Sala B, et al. Among authors: nichols j. Nature. 2019 Feb;566(7745):490-495. doi: 10.1038/s41586-019-0933-9. Epub 2019 Feb 20. Nature. 2019. PMID: 30787436 Free PMC article.

2

The NuRD component Mbd3 is required for pluripotency of embryonic stem cells.

Kaji K, Caballero IM, MacLeod R, Nichols J, Wilson VA, Hendrich B. Kaji K, et al. Among authors: nichols j. Nat Cell Biol. 2006 Mar;8(3):285-92. doi: 10.1038/ncb1372. Epub 2006 Feb 5. Nat Cell Biol. 2006. PMID: 16462733

3

Nanog safeguards pluripotency and mediates germline development.

Chambers I, Silva J, Colby D, Nichols J, Nijmeijer B, Robertson M, Vrana J, Jones K, Grotewold L, Smith A. Chambers I, et al. Among authors: nichols j. Nature. 2007 Dec 20;450(7173):1230-4. doi: 10.1038/nature06403. Nature. 2007. PMID: 18097409

4

Validated germline-competent embryonic stem cell lines from nonobese diabetic mice.

Nichols J, Jones K, Phillips JM, Newland SA, Roode M, Mansfield W, Smith A, Cooke A. Nichols J, et al. Nat Med. 2009 Jul;15(7):814-8. doi: 10.1038/nm.1996. Epub 2009 Jun 2. Nat Med. 2009. PMID: 19491843

5

LIF-independent JAK signalling to chromatin in embryonic stem cells uncovered from an adult stem cell disease.

Griffiths DS, Li J, Dawson MA, Trotter MW, Cheng YH, Smith AM, Mansfield W, Liu P, Kouzarides T, Nichols J, Bannister AJ, Green AR, Göttgens B. Griffiths DS, et al. Among authors: nichols j. Nat Cell Biol. 2011 Jan;13(1):13-21. doi: 10.1038/ncb2135. Epub 2010 Dec 12. Nat Cell Biol. 2011. PMID: 21151131 Free PMC article.

6

A defined Oct4 level governs cell state transitions of pluripotency entry and differentiation into all embryonic lineages.

Radzisheuskaya A, Chia Gle B, dos Santos RL, Theunissen TW, Castro LF, Nichols J, Silva JC. Radzisheuskaya A, et al. Among authors: nichols j. Nat Cell Biol. 2013 Jun;15(6):579-90. doi: 10.1038/ncb2742. Epub 2013 Apr 30. Nat Cell Biol. 2013. PMID: 23629142 Free PMC article.

7

A molecular basis for developmental plasticity in early mammalian embryos.

Martinez Arias A, Nichols J, Schröter C. Martinez Arias A, et al. Among authors: nichols j. Development. 2013 Sep;140(17):3499-510. doi: 10.1242/dev.091959. Development. 2013. PMID: 23942513 Review.

8

Rebuilding pluripotency from primordial germ cells.

Leitch HG, Nichols J, Humphreys P, Mulas C, Martello G, Lee C, Jones K, Surani MA, Smith A. Leitch HG, et al. Among authors: nichols j. Stem Cell Reports. 2013 Jun 4;1(1):66-78. doi: 10.1016/j.stemcr.2013.03.004. eCollection 2013. Stem Cell Reports. 2013. PMID: 24052943 Free PMC article.

9

Oct4 is required for lineage priming in the developing inner cell mass of the mouse blastocyst.

Le Bin GC, Muñoz-Descalzo S, Kurowski A, Leitch H, Lou X, Mansfield W, Etienne-Dumeau C, Grabole N, Mulas C, Niwa H, Hadjantonakis AK, Nichols J. Le Bin GC, et al. Among authors: nichols j. Development. 2014 Mar;141(5):1001-10. doi: 10.1242/dev.096875. Epub 2014 Feb 6. Development. 2014. PMID: 24504341 Free PMC article.

10

The ability of inner-cell-mass cells to self-renew as embryonic stem cells is acquired following epiblast specification.

Boroviak T, Loos R, Bertone P, Smith A, Nichols J. Boroviak T, et al. Among authors: nichols j. Nat Cell Biol. 2014 Jun;16(6):516-28. doi: 10.1038/ncb2965. Epub 2014 May 25. Nat Cell Biol. 2014. PMID: 24859004 Free PMC article.

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