Enhanced SIRT6 activity abrogates the neurotoxic phenotype of astrocytes expressing ALS-linked mutant SOD1.
Harlan BA, Pehar M, Killoy KM, Vargas MR.
Harlan BA, et al. Among authors: pehar m.
FASEB J. 2019 Jun;33(6):7084-7091. doi: 10.1096/fj.201802752R. Epub 2019 Mar 6.
FASEB J. 2019.
PMID: 30841754
Free PMC article.
Our results identify SIRT6 as a potential therapeutic target to prevent astrocyte-mediated motor neuron death in ALS.-Harlan, B. A., Pehar, M., Killoy, K. M., Vargas, M. R. Enhanced SIRT6 activity abrogates the neurotoxic phenotype of astrocytes expres …
Our results identify SIRT6 as a potential therapeutic target to prevent astrocyte-mediated motor neuron death in ALS.-Harlan, B. A., Peha …