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Enhanced SIRT6 activity abrogates the neurotoxic phenotype of astrocytes expressing ALS-linked mutant SOD1.
Harlan BA, Pehar M, Killoy KM, Vargas MR. Harlan BA, et al. Among authors: pehar m. FASEB J. 2019 Jun;33(6):7084-7091. doi: 10.1096/fj.201802752R. Epub 2019 Mar 6. FASEB J. 2019. PMID: 30841754 Free PMC article.
Our results identify SIRT6 as a potential therapeutic target to prevent astrocyte-mediated motor neuron death in ALS.-Harlan, B. A., Pehar, M., Killoy, K. M., Vargas, M. R. Enhanced SIRT6 activity abrogates the neurotoxic phenotype of astrocytes expres …
Our results identify SIRT6 as a potential therapeutic target to prevent astrocyte-mediated motor neuron death in ALS.-Harlan, B. A., Peha
A role for astrocytes in motor neuron loss in amyotrophic lateral sclerosis.
Barbeito LH, Pehar M, Cassina P, Vargas MR, Peluffo H, Viera L, Estévez AG, Beckman JS. Barbeito LH, et al. Among authors: pehar m. Brain Res Brain Res Rev. 2004 Dec;47(1-3):263-74. doi: 10.1016/j.brainresrev.2004.05.003. Brain Res Brain Res Rev. 2004. PMID: 15572176 Review.
74 results