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Macroencapsulated Human iPSC-Derived Pancreatic Progenitors Protect against STZ-Induced Hyperglycemia in Mice.
Haller C, Piccand J, De Franceschi F, Ohi Y, Bhoumik A, Boss C, De Marchi U, Jacot G, Metairon S, Descombes P, Wiederkehr A, Palini A, Bouche N, Steiner P, Kelly OG, R-C Kraus M. Haller C, et al. Among authors: wiederkehr a. Stem Cell Reports. 2019 Apr 9;12(4):787-800. doi: 10.1016/j.stemcr.2019.02.002. Epub 2019 Mar 7. Stem Cell Reports. 2019. PMID: 30853374 Free PMC article.
Modulation of the matrix redox signaling by mitochondrial Ca(2.).
Santo-Domingo J, Wiederkehr A, De Marchi U. Santo-Domingo J, et al. Among authors: wiederkehr a. World J Biol Chem. 2015 Nov 26;6(4):310-23. doi: 10.4331/wjbc.v6.i4.310. World J Biol Chem. 2015. PMID: 26629314 Free PMC article. Review.
Medium-chain fatty acids inhibit mitochondrial metabolism in astrocytes promoting astrocyte-neuron lactate and ketone body shuttle systems.
Thevenet J, De Marchi U, Domingo JS, Christinat N, Bultot L, Lefebvre G, Sakamoto K, Descombes P, Masoodi M, Wiederkehr A. Thevenet J, et al. Among authors: wiederkehr a. FASEB J. 2016 May;30(5):1913-26. doi: 10.1096/fj.201500182. Epub 2016 Feb 2. FASEB J. 2016. PMID: 26839375
Using single-cell imaging, we observed an acute pronounced reduction of the mitochondrial electrical potential and a concomitant drop of the NAD(P)H signal in astrocytes, but not in neurons. ...-Thevenet, J., De Marchi, U., Santo Domingo, J., Christinat, N., Bultot, L., Le …
Using single-cell imaging, we observed an acute pronounced reduction of the mitochondrial electrical potential and a concomitant drop …
Coordinated activation of mitochondrial respiration and exocytosis mediated by PKC signaling in pancreatic β cells.
Santo-Domingo J, Chareyron I, Dayon L, Núñez Galindo A, Cominetti O, Pilar Giner Giménez M, De Marchi U, Canto C, Kussmann M, Wiederkehr A. Santo-Domingo J, et al. Among authors: wiederkehr a. FASEB J. 2017 Mar;31(3):1028-1045. doi: 10.1096/fj.201600837R. Epub 2016 Dec 7. FASEB J. 2017. PMID: 27927723
Interactome analysis identified PKC, C-Raf, and ERK1/2 as the central phosphointeraction cluster. Prevention of ERK1/2 signaling by using a MEK1 inhibitor caused a marked decreased in phorbol 12-myristate 13-acetate-induced mitochondrial respiration. ...We conclude …
Interactome analysis identified PKC, C-Raf, and ERK1/2 as the central phosphointeraction cluster. Prevention of ERK1/2 signaling by using …
64 results