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Clinical, Diagnostic, and Treatment Characteristics of SDHA-Related Metastatic Pheochromocytoma and Paraganglioma.
Jha A, de Luna K, Balili CA, Millo C, Paraiso CA, Ling A, Gonzales MK, Viana B, Alrezk R, Adams KT, Tena I, Chen A, Neuzil J, Raygada M, Kebebew E, Taieb D, O'Dorisio MS, O'Dorisio T, Civelek AC, Stratakis CA, Mercado-Asis L, Pacak K. Jha A, et al. Among authors: neuzil j. Front Oncol. 2019 Feb 22;9:53. doi: 10.3389/fonc.2019.00053. eCollection 2019. Front Oncol. 2019. PMID: 30854332 Free PMC article.
Mitochondrial Complex II: At the Crossroads.
Bezawork-Geleta A, Rohlena J, Dong L, Pacak K, Neuzil J. Bezawork-Geleta A, et al. Among authors: neuzil j. Trends Biochem Sci. 2017 Apr;42(4):312-325. doi: 10.1016/j.tibs.2017.01.003. Epub 2017 Feb 7. Trends Biochem Sci. 2017. PMID: 28185716 Free PMC article. Review.
Succinate Mediates Tumorigenic Effects via Succinate Receptor 1: Potential for New Targeted Treatment Strategies in Succinate Dehydrogenase Deficient Paragangliomas.
Matlac DM, Hadrava Vanova K, Bechmann N, Richter S, Folberth J, Ghayee HK, Ge GB, Abunimer L, Wesley R, Aherrahrou R, Dona M, Martínez-Montes ÁM, Calsina B, Merino MJ, Schwaninger M, Deen PMT, Zhuang Z, Neuzil J, Pacak K, Lehnert H, Fliedner SMJ. Matlac DM, et al. Among authors: neuzil j. Front Endocrinol (Lausanne). 2021 Mar 12;12:589451. doi: 10.3389/fendo.2021.589451. eCollection 2021. Front Endocrinol (Lausanne). 2021. PMID: 33776908 Free PMC article.
Germline SUCLG2 Variants in Patients With Pheochromocytoma and Paraganglioma.
Hadrava Vanova K, Pang Y, Krobova L, Kraus M, Nahacka Z, Boukalova S, Pack SD, Zobalova R, Zhu J, Huynh TT, Jochmanova I, Uher O, Hubackova S, Dvorakova S, Garrett TJ, Ghayee HK, Wu X, Schuster B, Knapp PE, Frysak Z, Hartmann I, Nilubol N, Cerny J, Taieb D, Rohlena J, Neuzil J, Yang C, Pacak K. Hadrava Vanova K, et al. Among authors: neuzil j. J Natl Cancer Inst. 2022 Jan 11;114(1):130-138. doi: 10.1093/jnci/djab158. J Natl Cancer Inst. 2022. PMID: 34415331 Free PMC article.
Alternative assembly of respiratory complex II connects energy stress to metabolic checkpoints.
Bezawork-Geleta A, Wen H, Dong L, Yan B, Vider J, Boukalova S, Krobova L, Vanova K, Zobalova R, Sobol M, Hozak P, Novais SM, Caisova V, Abaffy P, Naraine R, Pang Y, Zaw T, Zhang P, Sindelka R, Kubista M, Zuryn S, Molloy MP, Berridge MV, Pacak K, Rohlena J, Park S, Neuzil J. Bezawork-Geleta A, et al. Among authors: neuzil j. Nat Commun. 2018 Jun 7;9(1):2221. doi: 10.1038/s41467-018-04603-z. Nat Commun. 2018. PMID: 29880867 Free PMC article.
Genetic impairment of succinate metabolism disrupts bioenergetic sensing in adrenal neuroendocrine cancer.
Gupta P, Strange K, Telange R, Guo A, Hatch H, Sobh A, Elie J, Carter AM, Totenhagen J, Tan C, Sonawane YA, Neuzil J, Natarajan A, Ovens AJ, Oakhill JS, Wiederhold T, Pacak K, Ghayee HK, Meijer L, Reddy S, Bibb JA. Gupta P, et al. Among authors: neuzil j. Cell Rep. 2022 Aug 16;40(7):111218. doi: 10.1016/j.celrep.2022.111218. Cell Rep. 2022. PMID: 35977518 Free PMC article.
Disordered-to-ordered transitions in assembly factors allow the complex II catalytic subunit to switch binding partners.
Sharma P, Maklashina E, Voehler M, Balintova S, Dvorakova S, Kraus M, Hadrava Vanova K, Nahacka Z, Zobalova R, Boukalova S, Cunatova K, Mracek T, Ghayee HK, Pacak K, Rohlena J, Neuzil J, Cecchini G, Iverson TM. Sharma P, et al. Among authors: neuzil j. Nat Commun. 2024 Jan 11;15(1):473. doi: 10.1038/s41467-023-44563-7. Nat Commun. 2024. PMID: 38212624 Free PMC article.
241 results