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Population genomic and evolutionary modelling analyses reveal a single major QTL for ivermectin drug resistance in the pathogenic nematode, Haemonchus contortus.
Doyle SR, Illingworth CJR, Laing R, Bartley DJ, Redman E, Martinelli A, Holroyd N, Morrison AA, Rezansoff A, Tracey A, Devaney E, Berriman M, Sargison N, Cotton JA, Gilleard JS. Doyle SR, et al. Among authors: devaney e. BMC Genomics. 2019 Mar 15;20(1):218. doi: 10.1186/s12864-019-5592-6. BMC Genomics. 2019. PMID: 30876405 Free PMC article.
The genome and transcriptome of Haemonchus contortus, a key model parasite for drug and vaccine discovery.
Laing R, Kikuchi T, Martinelli A, Tsai IJ, Beech RN, Redman E, Holroyd N, Bartley DJ, Beasley H, Britton C, Curran D, Devaney E, Gilabert A, Hunt M, Jackson F, Johnston SL, Kryukov I, Li K, Morrison AA, Reid AJ, Sargison N, Saunders GI, Wasmuth JD, Wolstenholme A, Berriman M, Gilleard JS, Cotton JA. Laing R, et al. Among authors: devaney e. Genome Biol. 2013 Aug 28;14(8):R88. doi: 10.1186/gb-2013-14-8-r88. Genome Biol. 2013. PMID: 23985316 Free PMC article.
Ivermectin - Old Drug, New Tricks?
Laing R, Gillan V, Devaney E. Laing R, et al. Among authors: devaney e. Trends Parasitol. 2017 Jun;33(6):463-472. doi: 10.1016/j.pt.2017.02.004. Epub 2017 Mar 9. Trends Parasitol. 2017. PMID: 28285851 Free PMC article. Review.
Increased Expression of a MicroRNA Correlates with Anthelmintic Resistance in Parasitic Nematodes.
Gillan V, Maitland K, Laing R, Gu H, Marks ND, Winter AD, Bartley D, Morrison A, Skuce PJ, Rezansoff AM, Gilleard JS, Martinelli A, Britton C, Devaney E. Gillan V, et al. Among authors: devaney e. Front Cell Infect Microbiol. 2017 Nov 6;7:452. doi: 10.3389/fcimb.2017.00452. eCollection 2017. Front Cell Infect Microbiol. 2017. PMID: 29209592 Free PMC article.
A Genome Resequencing-Based Genetic Map Reveals the Recombination Landscape of an Outbred Parasitic Nematode in the Presence of Polyploidy and Polyandry.
Doyle SR, Laing R, Bartley DJ, Britton C, Chaudhry U, Gilleard JS, Holroyd N, Mable BK, Maitland K, Morrison AA, Tait A, Tracey A, Berriman M, Devaney E, Cotton JA, Sargison ND. Doyle SR, et al. Among authors: devaney e. Genome Biol Evol. 2018 Feb 1;10(2):396-409. doi: 10.1093/gbe/evx269. Genome Biol Evol. 2018. PMID: 29267942 Free PMC article.
200 results