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Population genomic and evolutionary modelling analyses reveal a single major QTL for ivermectin drug resistance in the pathogenic nematode, Haemonchus contortus.
Doyle SR, Illingworth CJR, Laing R, Bartley DJ, Redman E, Martinelli A, Holroyd N, Morrison AA, Rezansoff A, Tracey A, Devaney E, Berriman M, Sargison N, Cotton JA, Gilleard JS. Doyle SR, et al. BMC Genomics. 2019 Mar 15;20(1):218. doi: 10.1186/s12864-019-5592-6. BMC Genomics. 2019. PMID: 30876405 Free PMC article.
The genome of Onchocerca volvulus, agent of river blindness.
Cotton JA, Bennuru S, Grote A, Harsha B, Tracey A, Beech R, Doyle SR, Dunn M, Hotopp JC, Holroyd N, Kikuchi T, Lambert O, Mhashilkar A, Mutowo P, Nursimulu N, Ribeiro JM, Rogers MB, Stanley E, Swapna LS, Tsai IJ, Unnasch TR, Voronin D, Parkinson J, Nutman TB, Ghedin E, Berriman M, Lustigman S. Cotton JA, et al. Among authors: doyle sr. Nat Microbiol. 2016 Nov 21;2:16216. doi: 10.1038/nmicrobiol.2016.216. Nat Microbiol. 2016. PMID: 27869790 Free PMC article.
A Genome Resequencing-Based Genetic Map Reveals the Recombination Landscape of an Outbred Parasitic Nematode in the Presence of Polyploidy and Polyandry.
Doyle SR, Laing R, Bartley DJ, Britton C, Chaudhry U, Gilleard JS, Holroyd N, Mable BK, Maitland K, Morrison AA, Tait A, Tracey A, Berriman M, Devaney E, Cotton JA, Sargison ND. Doyle SR, et al. Genome Biol Evol. 2018 Feb 1;10(2):396-409. doi: 10.1093/gbe/evx269. Genome Biol Evol. 2018. PMID: 29267942 Free PMC article.
Biology and genome of a newly discovered sibling species of Caenorhabditis elegans.
Kanzaki N, Tsai IJ, Tanaka R, Hunt VL, Liu D, Tsuyama K, Maeda Y, Namai S, Kumagai R, Tracey A, Holroyd N, Doyle SR, Woodruff GC, Murase K, Kitazume H, Chai C, Akagi A, Panda O, Ke HM, Schroeder FC, Wang J, Berriman M, Sternberg PW, Sugimoto A, Kikuchi T. Kanzaki N, et al. Among authors: doyle sr. Nat Commun. 2018 Aug 10;9(1):3216. doi: 10.1038/s41467-018-05712-5. Nat Commun. 2018. PMID: 30097582 Free PMC article.
Comparative genomics of the major parasitic worms.
International Helminth Genomes Consortium. International Helminth Genomes Consortium. Nat Genet. 2019 Jan;51(1):163-174. doi: 10.1038/s41588-018-0262-1. Epub 2018 Nov 5. Nat Genet. 2019. PMID: 30397333 Free PMC article.
Refugia and anthelmintic resistance: Concepts and challenges.
Hodgkinson JE, Kaplan RM, Kenyon F, Morgan ER, Park AW, Paterson S, Babayan SA, Beesley NJ, Britton C, Chaudhry U, Doyle SR, Ezenwa VO, Fenton A, Howell SB, Laing R, Mable BK, Matthews L, McIntyre J, Milne CE, Morrison TA, Prentice JC, Sargison ND, Williams DJL, Wolstenholme AJ, Devaney E. Hodgkinson JE, et al. Among authors: doyle sr. Int J Parasitol Drugs Drug Resist. 2019 Aug;10:51-57. doi: 10.1016/j.ijpddr.2019.05.001. Epub 2019 May 17. Int J Parasitol Drugs Drug Resist. 2019. PMID: 31125837 Free PMC article. Review.
The confounding effects of high genetic diversity on the determination and interpretation of differential gene expression analysis in the parasitic nematode Haemonchus contortus.
Rezansoff AM, Laing R, Martinelli A, Stasiuk S, Redman E, Bartley D, Holroyd N, Devaney E, Sargison ND, Doyle S, Cotton JA, Gilleard JS. Rezansoff AM, et al. Int J Parasitol. 2019 Oct;49(11):847-858. doi: 10.1016/j.ijpara.2019.05.012. Epub 2019 Sep 13. Int J Parasitol. 2019. PMID: 31525371 Free article.
Evaluation of DNA Extraction Methods on Individual Helminth Egg and Larval Stages for Whole-Genome Sequencing.
Doyle SR, Sankaranarayanan G, Allan F, Berger D, Jimenez Castro PD, Collins JB, Crellen T, Duque-Correa MA, Ellis P, Jaleta TG, Laing R, Maitland K, McCarthy C, Moundai T, Softley B, Thiele E, Ouakou PT, Tushabe JV, Webster JP, Weiss AJ, Lok J, Devaney E, Kaplan RM, Cotton JA, Berriman M, Holroyd N. Doyle SR, et al. Front Genet. 2019 Sep 20;10:826. doi: 10.3389/fgene.2019.00826. eCollection 2019. Front Genet. 2019. PMID: 31616465 Free PMC article.
89 results