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Adaptation to HIF1α Deletion in Hypoxic Cancer Cells by Upregulation of GLUT14 and Creatine Metabolism.
Valli A, Morotti M, Zois CE, Albers PK, Soga T, Feldinger K, Fischer R, Frejno M, McIntyre A, Bridges E, Haider S, Buffa FM, Baban D, Rodriguez M, Yanes O, Whittington HJ, Lake HA, Zervou S, Lygate CA, Kessler BM, Harris AL. Valli A, et al. Among authors: zervou s. Mol Cancer Res. 2019 Jul;17(7):1531-1544. doi: 10.1158/1541-7786.MCR-18-0315. Epub 2019 Mar 18. Mol Cancer Res. 2019. PMID: 30885992
Moderate elevation of intracellular creatine by targeting the creatine transporter protects mice from acute myocardial infarction.
Lygate CA, Bohl S, ten Hove M, Faller KM, Ostrowski PJ, Zervou S, Medway DJ, Aksentijevic D, Sebag-Montefiore L, Wallis J, Clarke K, Watkins H, Schneider JE, Neubauer S. Lygate CA, et al. Among authors: zervou s. Cardiovasc Res. 2012 Dec 1;96(3):466-75. doi: 10.1093/cvr/cvs272. Epub 2012 Aug 21. Cardiovasc Res. 2012. PMID: 22915766 Free PMC article.
Living without creatine: unchanged exercise capacity and response to chronic myocardial infarction in creatine-deficient mice.
Lygate CA, Aksentijevic D, Dawson D, ten Hove M, Phillips D, de Bono JP, Medway DJ, Sebag-Montefiore L, Hunyor I, Channon KM, Clarke K, Zervou S, Watkins H, Balaban RS, Neubauer S. Lygate CA, et al. Among authors: zervou s. Circ Res. 2013 Mar 15;112(6):945-55. doi: 10.1161/CIRCRESAHA.112.300725. Epub 2013 Jan 16. Circ Res. 2013. PMID: 23325497 Free PMC article.
Augmentation of Creatine in the Heart.
Zervou S, Whittington HJ, Russell AJ, Lygate CA. Zervou S, et al. Mini Rev Med Chem. 2016;16(1):19-28. doi: 10.2174/1389557515666150722102151. Mini Rev Med Chem. 2016. PMID: 26202199 Free PMC article. Review.
62 results