Pearson KM - Search Results

1

Use of a Bile Salt Export Pump Knockdown Rat Susceptibility Model to Interrogate Mechanism of Drug-Induced Liver Toxicity.

Li Y, Evers R, Hafey MJ, Cheon K, Duong H, Lynch D, LaFranco-Scheuch L, Pacchione S, Tamburino AM, Tanis KQ, Geddes K, Holder D, Zhang NR, Kang W, Gonzalez RJ, Galijatovic-Idrizbegovic A, Pearson KM, Lebron JA, Glaab WE, Sistare FD. Li Y, et al. Among authors: pearson km. Toxicol Sci. 2019 Jul 1;170(1):180-198. doi: 10.1093/toxsci/kfz079. Toxicol Sci. 2019. PMID: 30903168

2

Inhibin B response to testicular toxicants hexachlorophene, ethane dimethane sulfonate, di-(n-butyl)-phthalate, nitrofurazone, DL-ethionine, 17-alpha ethinylestradiol, 2,5-hexanedione, or carbendazim following short-term dosing in male rats.

Erdos Z, Pearson K, Goedken M, Menzel K, Sistare FD, Glaab WE, Saldutti LP. Erdos Z, et al. Birth Defects Res B Dev Reprod Toxicol. 2013 Feb;98(1):41-53. doi: 10.1002/bdrb.21035. Epub 2013 Jan 24. Birth Defects Res B Dev Reprod Toxicol. 2013. PMID: 23348767

3

AhR Activation in Pharmaceutical Development: Applying Liver Gene Expression Biomarker Thresholds to Identify Doses Associated With Tumorigenic Risks in Rats.

Qin C, Aslamkhan AG, Pearson K, Tanis KQ, Podtelezhnikov A, Frank E, Pacchione S, Pippert T, Glaab WE, Sistare FD. Qin C, et al. Toxicol Sci. 2019 Sep 1;171(1):46-55. doi: 10.1093/toxsci/kfz125. Toxicol Sci. 2019. PMID: 31127949

4

Can Galactose Be Converted to Glucose in HepG2 Cells? Improving the in Vitro Mitochondrial Toxicity Assay for the Assessment of Drug Induced Liver Injury.

Xu Q, Liu L, Vu H, Kuhls M, Aslamkhan AG, Liaw A, Yu Y, Kaczor A, Ruth M, Wei C, Imredy J, Lebron J, Pearson K, Gonzalez R, Mitra K, Sistare FD. Xu Q, et al. Chem Res Toxicol. 2019 Aug 19;32(8):1528-1544. doi: 10.1021/acs.chemrestox.9b00033. Epub 2019 Jul 18. Chem Res Toxicol. 2019. PMID: 31271030

5

Quantitative Transcriptional Biomarkers of Xenobiotic Receptor Activation in Rat Liver for the Early Assessment of Drug Safety Liabilities.

Podtelezhnikov AA, Monroe JJ, Aslamkhan AG, Pearson K, Qin C, Tamburino AM, Loboda AP, Glaab WE, Sistare FD, Tanis KQ. Podtelezhnikov AA, et al. Toxicol Sci. 2020 May 1;175(1):98-112. doi: 10.1093/toxsci/kfaa026. Toxicol Sci. 2020. PMID: 32119089

6

Characterization of indoleamine-2,3-dioxygenase 1, tryptophan-2,3-dioxygenase, and Ido1/Tdo2 knockout mice.

Aslamkhan AG, Xu Q, Loughlin A, Vu H, Pacchione S, Bhatt B, Garfinkel I, Styring TG, LaFranco-Scheuch L, Pearson K, Reynolds S, Li N, Zhou H, Miller JR, Solban N, Bass A, Glaab WE. Aslamkhan AG, et al. Toxicol Appl Pharmacol. 2020 Nov 1;406:115216. doi: 10.1016/j.taap.2020.115216. Epub 2020 Aug 29. Toxicol Appl Pharmacol. 2020. PMID: 32871117

7

The application of cytokeratin-18 as a biomarker for drug-induced liver injury.

Korver S, Bowen J, Pearson K, Gonzalez RJ, French N, Park K, Jenkins R, Goldring C. Korver S, et al. Arch Toxicol. 2021 Nov;95(11):3435-3448. doi: 10.1007/s00204-021-03121-0. Epub 2021 Jul 29. Arch Toxicol. 2021. PMID: 34322741 Free PMC article. Review.

8

Rapid and Definitive Identification of Cyclic Peptide Soft Spots by Isotope-Labeled Reductive Dimethylation and Mass Spectrometry Fragmentation.

Feng Y, Qirjollari A, Fawaz MV, Cancilla MT, Gonzalez RJ, Pearson K. Feng Y, et al. Anal Chem. 2024 May 14;96(19):7756-7762. doi: 10.1021/acs.analchem.4c01372. Epub 2024 May 1. Anal Chem. 2024. PMID: 38690743

9

Effects of LRRK2 Inhibitors in Nonhuman Primates.

Miller GK, Kuruvilla S, Jacob B, LaFranco-Scheuch L, Bakthavatchalu V, Flor J, Flor K, Ziegler J, Reichard C, Manfre P, Firner S, McNutt T, Quay D, Bellum S, Doto G, Ciaccio PJ, Pearson K, Valentine J, Fuller P, Fell M, Tsuchiya T, Williamson T, Wollenberg G. Miller GK, et al. Toxicol Pathol. 2023 Jul;51(5):232-245. doi: 10.1177/01926233231205895. Epub 2023 Nov 2. Toxicol Pathol. 2023. PMID: 37916535

10

Image-guided drainage of tuboovarian abscesses of gastrointestinal or genitourinary origin: a retrospective analysis.

Levenson RB, Pearson KM, Saokar A, Lee SI, Mueller PR, Hahn PF. Levenson RB, et al. Among authors: pearson km. J Vasc Interv Radiol. 2011 May;22(5):678-86. doi: 10.1016/j.jvir.2010.10.032. Epub 2011 Mar 21. J Vasc Interv Radiol. 2011. PMID: 21419651

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