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SPOP targets the immune transcription factor IRF1 for proteasomal degradation.
Schwartz I, Vunjak M, Budroni V, Cantoran García A, Mastrovito M, Soderholm A, Hinterndorfer M, de Almeida M, Hacker K, Wang J, Froussios K, Jude J, Decker T, Zuber J, Versteeg GA. Schwartz I, et al. Among authors: froussios k. Elife. 2023 Aug 25;12:e89951. doi: 10.7554/eLife.89951. Elife. 2023. PMID: 37622993 Free PMC article.
HUWE1 controls tristetraprolin proteasomal degradation by regulating its phosphorylation.
Scinicariello S, Soderholm A, Schäfer M, Shulkina A, Schwartz I, Hacker K, Gogova R, Kalis R, Froussios K, Budroni V, Bestehorn A, Clausen T, Kovarik P, Zuber J, Versteeg GA. Scinicariello S, et al. Among authors: froussios k. Elife. 2023 Mar 24;12:e83159. doi: 10.7554/eLife.83159. Elife. 2023. PMID: 36961408 Free PMC article.
Isolating live cell clones from barcoded populations using CRISPRa-inducible reporters.
Umkehrer C, Holstein F, Formenti L, Jude J, Froussios K, Neumann T, Cronin SM, Haas L, Lipp JJ, Burkard TR, Fellner M, Wiesner T, Zuber J, Obenauf AC. Umkehrer C, et al. Among authors: froussios k. Nat Biotechnol. 2021 Feb;39(2):174-178. doi: 10.1038/s41587-020-0614-0. Epub 2020 Jul 27. Nat Biotechnol. 2021. PMID: 32719478