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Targeting senescent cells alleviates obesity-induced metabolic dysfunction.
Palmer AK, Xu M, Zhu Y, Pirtskhalava T, Weivoda MM, Hachfeld CM, Prata LG, van Dijk TH, Verkade E, Casaclang-Verzosa G, Johnson KO, Cubro H, Doornebal EJ, Ogrodnik M, Jurk D, Jensen MD, Chini EN, Miller JD, Matveyenko A, Stout MB, Schafer MJ, White TA, Hickson LJ, Demaria M, Garovic V, Grande J, Arriaga EA, Kuipers F, von Zglinicki T, LeBrasseur NK, Campisi J, Tchkonia T, Kirkland JL. Palmer AK, et al. Among authors: kuipers f. Aging Cell. 2019 Jun;18(3):e12950. doi: 10.1111/acel.12950. Epub 2019 Mar 25. Aging Cell. 2019. PMID: 30907060 Free PMC article.
Hepatic de novo synthesis of glucose 6-phosphate is not affected in peroxisome proliferator-activated receptor alpha-deficient mice but is preferentially directed toward hepatic glycogen stores after a short term fast.
Bandsma RH, Van Dijk TH, Harmsel At At, Kok T, Reijngoud DJ, Staels B, Kuipers F. Bandsma RH, et al. Among authors: kuipers f. J Biol Chem. 2004 Mar 5;279(10):8930-7. doi: 10.1074/jbc.M310067200. Epub 2003 Dec 19. J Biol Chem. 2004. PMID: 14688286 Free article.
Differential effects of pharmacological liver X receptor activation on hepatic and peripheral insulin sensitivity in lean and ob/ob mice.
Grefhorst A, van Dijk TH, Hammer A, van der Sluijs FH, Havinga R, Havekes LM, Romijn JA, Groot PH, Reijngoud DJ, Kuipers F. Grefhorst A, et al. Among authors: kuipers f. Am J Physiol Endocrinol Metab. 2005 Nov;289(5):E829-38. doi: 10.1152/ajpendo.00165.2005. Epub 2005 Jun 7. Am J Physiol Endocrinol Metab. 2005. PMID: 15941783 Free article.
The farnesoid X receptor modulates adiposity and peripheral insulin sensitivity in mice.
Cariou B, van Harmelen K, Duran-Sandoval D, van Dijk TH, Grefhorst A, Abdelkarim M, Caron S, Torpier G, Fruchart JC, Gonzalez FJ, Kuipers F, Staels B. Cariou B, et al. Among authors: kuipers f. J Biol Chem. 2006 Apr 21;281(16):11039-49. doi: 10.1074/jbc.M510258200. Epub 2006 Jan 30. J Biol Chem. 2006. PMID: 16446356 Free article.
Lxralpha deficiency hampers the hepatic adaptive response to fasting in mice.
Oosterveer MH, van Dijk TH, Grefhorst A, Bloks VW, Havinga R, Kuipers F, Reijngoud DJ. Oosterveer MH, et al. Among authors: kuipers f. J Biol Chem. 2008 Sep 12;283(37):25437-25445. doi: 10.1074/jbc.M801922200. Epub 2008 Jul 8. J Biol Chem. 2008. PMID: 18611859 Free article.
Fetal liver X receptor activation acutely induces lipogenesis but does not affect plasma lipid response to a high-fat diet in adult mice.
van Straten EM, van Meer H, Huijkman NC, van Dijk TH, Baller JF, Verkade HJ, Kuipers F, Plösch T. van Straten EM, et al. Among authors: kuipers f. Am J Physiol Endocrinol Metab. 2009 Nov;297(5):E1171-8. doi: 10.1152/ajpendo.00021.2009. Epub 2009 Sep 1. Am J Physiol Endocrinol Metab. 2009. PMID: 19724022 Free article.
484 results