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Long-term efficacy and safety of obeticholic acid for patients with primary biliary cholangitis: 3-year results of an international open-label extension study.
Trauner M, Nevens F, Shiffman ML, Drenth JPH, Bowlus CL, Vargas V, Andreone P, Hirschfield GM, Pencek R, Malecha ES, MacConell L, Shapiro D. Trauner M, et al. Lancet Gastroenterol Hepatol. 2019 Jun;4(6):445-453. doi: 10.1016/S2468-1253(19)30094-9. Epub 2019 Mar 26. Lancet Gastroenterol Hepatol. 2019. PMID: 30922873 Clinical Trial.
24-norUrsodeoxycholic acid is superior to ursodeoxycholic acid in the treatment of sclerosing cholangitis in Mdr2 (Abcb4) knockout mice.
Fickert P, Wagner M, Marschall HU, Fuchsbichler A, Zollner G, Tsybrovskyy O, Zatloukal K, Liu J, Waalkes MP, Cover C, Denk H, Hofmann AF, Jaeschke H, Trauner M. Fickert P, et al. Among authors: trauner m. Gastroenterology. 2006 Feb;130(2):465-81. doi: 10.1053/j.gastro.2005.10.018. Gastroenterology. 2006. PMID: 16472600
Will we ever model PSC? - "it's hard to be a PSC model!".
Pollheimer MJ, Trauner M, Fickert P. Pollheimer MJ, et al. Among authors: trauner m. Clin Res Hepatol Gastroenterol. 2011 Dec;35(12):792-804. doi: 10.1016/j.clinre.2011.04.014. Epub 2011 Jun 23. Clin Res Hepatol Gastroenterol. 2011. PMID: 21703962 Review.
Characterization of animal models for primary sclerosing cholangitis (PSC).
Fickert P, Pollheimer MJ, Beuers U, Lackner C, Hirschfield G, Housset C, Keitel V, Schramm C, Marschall HU, Karlsen TH, Melum E, Kaser A, Eksteen B, Strazzabosco M, Manns M, Trauner M; International PSC Study Group (IPSCSG). Fickert P, et al. Among authors: trauner m. J Hepatol. 2014 Jun;60(6):1290-303. doi: 10.1016/j.jhep.2014.02.006. Epub 2014 Feb 19. J Hepatol. 2014. PMID: 24560657 Free PMC article. Review.
Fibrate treatment for primary biliary cirrhosis.
Cuperus FJ, Halilbasic E, Trauner M. Cuperus FJ, et al. Among authors: trauner m. Curr Opin Gastroenterol. 2014 May;30(3):279-86. doi: 10.1097/MOG.0000000000000056. Curr Opin Gastroenterol. 2014. PMID: 24625898 Review.
24-nor-ursodeoxycholic acid ameliorates inflammatory response and liver fibrosis in a murine model of hepatic schistosomiasis.
Sombetzki M, Fuchs CD, Fickert P, Österreicher CH, Mueller M, Claudel T, Loebermann M, Engelmann R, Langner C, Sahin E, Schwinge D, Guenther ND, Schramm C, Mueller-Hilke B, Reisinger EC, Trauner M. Sombetzki M, et al. Among authors: trauner m. J Hepatol. 2015 Apr;62(4):871-8. doi: 10.1016/j.jhep.2014.11.020. Epub 2014 Nov 21. J Hepatol. 2015. PMID: 25463533 Free PMC article.
Efficacy of obeticholic acid in patients with primary biliary cirrhosis and inadequate response to ursodeoxycholic acid.
Hirschfield GM, Mason A, Luketic V, Lindor K, Gordon SC, Mayo M, Kowdley KV, Vincent C, Bodhenheimer HC Jr, Parés A, Trauner M, Marschall HU, Adorini L, Sciacca C, Beecher-Jones T, Castelloe E, Böhm O, Shapiro D. Hirschfield GM, et al. Among authors: trauner m. Gastroenterology. 2015 Apr;148(4):751-61.e8. doi: 10.1053/j.gastro.2014.12.005. Epub 2014 Dec 11. Gastroenterology. 2015. PMID: 25500425 Free article. Clinical Trial.
780 results