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Page 1
Evidence of causal effect of major depression on alcohol dependence: findings from the psychiatric genomics consortium.
Polimanti R, Peterson RE, Ong JS, MacGregor S, Edwards AC, Clarke TK, Frank J, Gerring Z, Gillespie NA, Lind PA, Maes HH, Martin NG, Mbarek H, Medland SE, Streit F; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; Agrawal A, Edenberg HJ, Kendler KS, Lewis CM, Sullivan PF, Wray NR, Gelernter J, Derks EM. Polimanti R, et al. Among authors: edenberg hj. Psychol Med. 2019 May;49(7):1218-1226. doi: 10.1017/S0033291719000667. Epub 2019 Apr 1. Psychol Med. 2019. PMID: 30929657 Free PMC article.
Evidence of common and specific genetic effects: association of the muscarinic acetylcholine receptor M2 (CHRM2) gene with alcohol dependence and major depressive syndrome.
Wang JC, Hinrichs AL, Stock H, Budde J, Allen R, Bertelsen S, Kwon JM, Wu W, Dick DM, Rice J, Jones K, Nurnberger JI Jr, Tischfield J, Porjesz B, Edenberg HJ, Hesselbrock V, Crowe R, Schuckit M, Begleiter H, Reich T, Goate AM, Bierut LJ. Wang JC, et al. Among authors: edenberg hj. Hum Mol Genet. 2004 Sep 1;13(17):1903-11. doi: 10.1093/hmg/ddh194. Epub 2004 Jun 30. Hum Mol Genet. 2004. PMID: 15229186
Association of the kappa-opioid system with alcohol dependence.
Xuei X, Dick D, Flury-Wetherill L, Tian HJ, Agrawal A, Bierut L, Goate A, Bucholz K, Schuckit M, Nurnberger J Jr, Tischfield J, Kuperman S, Porjesz B, Begleiter H, Foroud T, Edenberg HJ. Xuei X, et al. Among authors: edenberg hj. Mol Psychiatry. 2006 Nov;11(11):1016-24. doi: 10.1038/sj.mp.4001882. Epub 2006 Aug 22. Mol Psychiatry. 2006. PMID: 16924269
Alcohol dependence with comorbid drug dependence: genetic and phenotypic associations suggest a more severe form of the disorder with stronger genetic contribution to risk.
Dick DM, Agrawal A, Wang JC, Hinrichs A, Bertelsen S, Bucholz KK, Schuckit M, Kramer J, Nurnberger J Jr, Tischfield J, Edenberg HJ, Goate A, Bierut LJ. Dick DM, et al. Among authors: edenberg hj. Addiction. 2007 Jul;102(7):1131-9. doi: 10.1111/j.1360-0443.2007.01871.x. Addiction. 2007. PMID: 17567401
Genetic variation in the CHRNA5 gene affects mRNA levels and is associated with risk for alcohol dependence.
Wang JC, Grucza R, Cruchaga C, Hinrichs AL, Bertelsen S, Budde JP, Fox L, Goldstein E, Reyes O, Saccone N, Saccone S, Xuei X, Bucholz K, Kuperman S, Nurnberger J Jr, Rice JP, Schuckit M, Tischfield J, Hesselbrock V, Porjesz B, Edenberg HJ, Bierut LJ, Goate AM. Wang JC, et al. Among authors: edenberg hj. Mol Psychiatry. 2009 May;14(5):501-10. doi: 10.1038/mp.2008.42. Epub 2008 Apr 15. Mol Psychiatry. 2009. PMID: 18414406 Free PMC article.
Evidence for association between polymorphisms in the cannabinoid receptor 1 (CNR1) gene and cannabis dependence.
Agrawal A, Wetherill L, Dick DM, Xuei X, Hinrichs A, Hesselbrock V, Kramer J, Nurnberger JI Jr, Schuckit M, Bierut LJ, Edenberg HJ, Foroud T. Agrawal A, et al. Among authors: edenberg hj. Am J Med Genet B Neuropsychiatr Genet. 2009 Jul 5;150B(5):736-40. doi: 10.1002/ajmg.b.30881. Am J Med Genet B Neuropsychiatr Genet. 2009. PMID: 19016476 Free PMC article.
A genome-wide association study of alcohol dependence.
Bierut LJ, Agrawal A, Bucholz KK, Doheny KF, Laurie C, Pugh E, Fisher S, Fox L, Howells W, Bertelsen S, Hinrichs AL, Almasy L, Breslau N, Culverhouse RC, Dick DM, Edenberg HJ, Foroud T, Grucza RA, Hatsukami D, Hesselbrock V, Johnson EO, Kramer J, Krueger RF, Kuperman S, Lynskey M, Mann K, Neuman RJ, Nöthen MM, Nurnberger JI Jr, Porjesz B, Ridinger M, Saccone NL, Saccone SF, Schuckit MA, Tischfield JA, Wang JC, Rietschel M, Goate AM, Rice JP; Gene, Environment Association Studies Consortium. Bierut LJ, et al. Among authors: edenberg hj. Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):5082-7. doi: 10.1073/pnas.0911109107. Epub 2010 Mar 2. Proc Natl Acad Sci U S A. 2010. PMID: 20202923 Free PMC article.
A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts.
Kalsi G, Kuo PH, Aliev F, Alexander J, McMichael O, Patterson DG, Walsh D, Zhao Z, Schuckit M, Nurnberger J Jr, Edenberg H, Kramer J, Hesselbrock V, Tischfield JA, Vladimirov V, Prescott CA, Dick DM, Kendler KS, Riley BP. Kalsi G, et al. Hum Mol Genet. 2010 Jun 15;19(12):2497-506. doi: 10.1093/hmg/ddq112. Epub 2010 Mar 23. Hum Mol Genet. 2010. PMID: 20332099 Free PMC article.
565 results