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Relative interfacial cleavage energetics of protein complexes revealed by surface collisions.
Proc Natl Acad Sci U S A. 2019 Apr 23;116(17):8143-8148. doi: 10.1073/pnas.1817632116. Epub 2019 Apr 3.
Proc Natl Acad Sci U S A. 2019.
PMID: 30944216
Free PMC article.
Confirmation of intersubunit connectivity and topology of designed protein complexes by native MS.
Sahasrabuddhe A, Hsia Y, Busch F, Sheffler W, King NP, Baker D, Wysocki VH.
Sahasrabuddhe A, et al.
Proc Natl Acad Sci U S A. 2018 Feb 6;115(6):1268-1273. doi: 10.1073/pnas.1713646115. Epub 2018 Jan 19.
Proc Natl Acad Sci U S A. 2018.
PMID: 29351988
Free PMC article.
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Generation of ordered protein assemblies using rigid three-body fusion.
Vulovic I, Yao Q, Park YJ, Courbet A, Norris A, Busch F, Sahasrabuddhe A, Merten H, Sahtoe DD, Ueda G, Fallas JA, Weaver SJ, Hsia Y, Langan RA, Plückthun A, Wysocki VH, Veesler D, Jensen GJ, Baker D.
Vulovic I, et al.
Proc Natl Acad Sci U S A. 2021 Jun 8;118(23):e2015037118. doi: 10.1073/pnas.2015037118.
Proc Natl Acad Sci U S A. 2021.
PMID: 34074752
Free PMC article.
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Rapid online buffer exchange for screening of proteins, protein complexes and cell lysates by native mass spectrometry.
VanAernum ZL, Busch F, Jones BJ, Jia M, Chen Z, Boyken SE, Sahasrabuddhe A, Baker D, Wysocki VH.
VanAernum ZL, et al.
Nat Protoc. 2020 Mar;15(3):1132-1157. doi: 10.1038/s41596-019-0281-0. Epub 2020 Jan 31.
Nat Protoc. 2020.
PMID: 32005983
Free PMC article.
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Programmable design of orthogonal protein heterodimers.
Chen Z, Boyken SE, Jia M, Busch F, Flores-Solis D, Bick MJ, Lu P, VanAernum ZL, Sahasrabuddhe A, Langan RA, Bermeo S, Brunette TJ, Mulligan VK, Carter LP, DiMaio F, Sgourakis NG, Wysocki VH, Baker D.
Chen Z, et al.
Nature. 2019 Jan;565(7737):106-111. doi: 10.1038/s41586-018-0802-y. Epub 2018 Dec 19.
Nature. 2019.
PMID: 30568301
Free PMC article.
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De novo design of tunable, pH-driven conformational changes.
Boyken SE, Benhaim MA, Busch F, Jia M, Bick MJ, Choi H, Klima JC, Chen Z, Walkey C, Mileant A, Sahasrabuddhe A, Wei KY, Hodge EA, Byron S, Quijano-Rubio A, Sankaran B, King NP, Lippincott-Schwartz J, Wysocki VH, Lee KK, Baker D.
Boyken SE, et al.
Science. 2019 May 17;364(6441):658-664. doi: 10.1126/science.aav7897.
Science. 2019.
PMID: 31097662
Free PMC article.
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Development of a High-Throughput Affinity Mass Spectrometry (AMS) Platform Using Laser Diode Thermal Desorption Ionization Coupled to Mass Spectrometry (LDTD-MS).
Sahasrabuddhe A, Oakley D, Chen K, McCarter JD.
Sahasrabuddhe A, et al.
SLAS Discov. 2021 Feb;26(2):230-241. doi: 10.1177/2472555220979596. Epub 2020 Dec 17.
SLAS Discov. 2021.
PMID: 33334237
Free article.
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