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Page 1
Safety and efficacy of VRC01 broadly neutralising antibodies in adults with acutely treated HIV (RV397): a phase 2, randomised, double-blind, placebo-controlled trial.
Crowell TA, Colby DJ, Pinyakorn S, Sacdalan C, Pagliuzza A, Intasan J, Benjapornpong K, Tangnaree K, Chomchey N, Kroon E, de Souza MS, Tovanabutra S, Rolland M, Eller MA, Paquin-Proulx D, Bolton DL, Tokarev A, Thomas R, Takata H, Trautmann L, Krebs SJ, Modjarrad K, McDermott AB, Bailer RT, Doria-Rose N, Patel B, Gorelick RJ, Fullmer BA, Schuetz A, Grandin PV, O'Connell RJ, Ledgerwood JE, Graham BS, Tressler R, Mascola JR, Chomont N, Michael NL, Robb ML, Phanuphak N, Ananworanich J; RV397 Study Group. Crowell TA, et al. Among authors: benjapornpong k. Lancet HIV. 2019 May;6(5):e297-e306. doi: 10.1016/S2352-3018(19)30053-0. Epub 2019 Apr 15. Lancet HIV. 2019. PMID: 31000477 Free PMC article. Clinical Trial.
Neutralizing antibody VRC01 failed to select for HIV-1 mutations upon viral rebound.
Cale EM, Bai H, Bose M, Messina MA, Colby DJ, Sanders-Buell E, Dearlove B, Li Y, Engeman E, Silas D, O'Sullivan AM, Mann B, Pinyakorn S, Intasan J, Benjapornpong K, Sacdalan C, Kroon E, Phanuphak N, Gramzinski R, Vasan S, Robb ML, Michael NL, Lynch RM, Bailer RT, Pagliuzza A, Chomont N, Pegu A, Doria-Rose NA, Trautmann L, Crowell TA, Mascola JR, Ananworanich J, Tovanabutra S, Rolland M; RV397 Study Group. Cale EM, et al. Among authors: benjapornpong k. J Clin Invest. 2020 Jun 1;130(6):3299-3304. doi: 10.1172/JCI134395. J Clin Invest. 2020. PMID: 32182219 Free PMC article. Clinical Trial.
Central Nervous System Safety During Brief Analytic Treatment Interruption of Antiretroviral Therapy Within 4 Human Immunodeficiency Virus Remission Trials: An Observational Study in Acutely Treated People Living With Human Immunodeficiency Virus.
Hellmuth J, Muccini C, Colby DJ, Kroon E, de Souza M, Crowell TA, Chan P, Sacdalan C, Intasan J, Benjapornpong K, Tipsuk S, Puttamaswin S, Chomchey N, Valcour V, Sarnecki M, Tomaka F, Krebs SJ, Slike BM, Jagodzinski LL, Dumrongpisutikul N, Sailasuta N, Samboju V, Michael NL, Robb ML, Vasan S, Ananworanich J, Phanuphak P, Phanuphak N, Paul R, Spudich S. Hellmuth J, et al. Among authors: benjapornpong k. Clin Infect Dis. 2021 Oct 5;73(7):e1885-e1892. doi: 10.1093/cid/ciaa1344. Clin Infect Dis. 2021. PMID: 32916708 Free PMC article.
Long-term antiretroviral therapy initiated in acute HIV infection prevents residual dysfunction of HIV-specific CD8+ T cells.
Takata H, Kakazu JC, Mitchell JL, Kroon E, Colby DJ, Sacdalan C, Bai H, Ehrenberg PK, Geretz A, Buranapraditkun S, Pinyakorn S, Intasan J, Tipsuk S, Suttichom D, Prueksakaew P, Chalermchai T, Chomchey N, Phanuphak N, de Souza M, Michael NL, Robb ML, Haddad EK, Crowell TA, Vasan S, Valcour VG, Douek DC, Thomas R, Rolland M, Chomont N, Ananworanich J, Trautmann L; RV254/SEARCH010, RV304/ SEARCH013, and SEARCH011 study groups. Takata H, et al. EBioMedicine. 2022 Oct;84:104253. doi: 10.1016/j.ebiom.2022.104253. Epub 2022 Sep 8. EBioMedicine. 2022. PMID: 36088683 Free PMC article.
Declining trend in transmitted drug resistance detected in a prospective cohort study of acute HIV infection in Bangkok, Thailand.
Colby DJ, Crowell TA, Sirivichayakul S, Pinyakorn S, Kroon E, Benjapornpong K, Intasan J, Trichavaroj R, Tovanabutra S, Robb M, Phanuphak P, Ananworanich J, Phanuphak N; Search 010/RV 254 Study Group. Colby DJ, et al. Among authors: benjapornpong k. J Int AIDS Soc. 2016 Oct 31;19(1):20966. doi: 10.7448/IAS.19.1.20966. eCollection 2016. J Int AIDS Soc. 2016. PMID: 27802846 Free PMC article.
Normalization of Soluble CD163 Levels After Institution of Antiretroviral Therapy During Acute HIV Infection Tracks with Fewer Neurological Abnormalities.
D'Antoni ML, Byron MM, Chan P, Sailasuta N, Sacdalan C, Sithinamsuwan P, Tipsuk S, Pinyakorn S, Kroon E, Slike BM, Krebs SJ, Khadka VS, Chalermchai T, Kallianpur KJ, Robb M, Spudich S, Valcour V, Ananworanich J, Ndhlovu LC; RV254/SEARCH010, SEARCH011, and RV304/SEARCH013 Study Groups. D'Antoni ML, et al. J Infect Dis. 2018 Sep 22;218(9):1453-1463. doi: 10.1093/infdis/jiy337. J Infect Dis. 2018. PMID: 29868826 Free PMC article. Clinical Trial.
Plasmacytoid dendritic cells sense HIV replication before detectable viremia following treatment interruption.
Mitchell JL, Takata H, Muir R, Colby DJ, Kroon E, Crowell TA, Sacdalan C, Pinyakorn S, Puttamaswin S, Benjapornpong K, Trichavaroj R, Tressler RL, Fox L, Polonis VR, Bolton DL, Maldarelli F, Lewin SR, Haddad EK, Phanuphak P, Robb ML, Michael NL, de Souza M, Phanuphak N, Ananworanich J, Trautmann L; RV397, RV411, and RV254 Study Groups. Mitchell JL, et al. Among authors: benjapornpong k. J Clin Invest. 2020 Jun 1;130(6):2845-2858. doi: 10.1172/JCI130597. J Clin Invest. 2020. PMID: 32017709 Free PMC article. Clinical Trial.
Impact of Acute HIV Infection and Early Antiretroviral Therapy on the Human Gut Microbiome.
Sortino O, Phanuphak N, Schuetz A, Ortiz AM, Chomchey N, Belkaid Y, Davis J, Mystakelis HA, Quiñones M, Deleage C, Ingram B, Rerknimitr R, Pinyakorn S, Rupert A, Robb ML, Ananworanich J, Brenchley J, Sereti I; RV254/SEARCH010 Study Group. Sortino O, et al. Open Forum Infect Dis. 2019 Aug 21;7(12):ofz367. doi: 10.1093/ofid/ofz367. eCollection 2020 Dec. Open Forum Infect Dis. 2019. PMID: 33324725 Free PMC article.
Attitudes About Analytic Treatment Interruption (ATI) in HIV Remission Trials with Different Antiretroviral Therapy (ART) Resumption Criteria.
Peay HL, Rennie S, Cadigan RJ, Gwaltney A, Jupimai T, Phanuphak N, Kroon E, Colby DJ, Ormsby N, Isaacson SC, Vasan S, Sacdalan C, Prueksakaew P, Benjapornpong K, Ananworanich J, Henderson GE. Peay HL, et al. Among authors: benjapornpong k. AIDS Behav. 2022 May;26(5):1504-1516. doi: 10.1007/s10461-021-03504-5. Epub 2022 Jan 8. AIDS Behav. 2022. PMID: 34997386 Free PMC article.
Structural and functional brain imaging in acute HIV.
Samboju V, Philippi CL, Chan P, Cobigo Y, Fletcher JLK, Robb M, Hellmuth J, Benjapornpong K, Dumrongpisutikul N, Pothisri M, Paul R, Ananworanich J, Spudich S, Valcour V; SEARCH 010/RV254; RV304 protocol teams. Samboju V, et al. Among authors: benjapornpong k. Neuroimage Clin. 2018 Jul 27;20:327-335. doi: 10.1016/j.nicl.2018.07.024. eCollection 2018. Neuroimage Clin. 2018. PMID: 30101063 Free PMC article.
16 results