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Safety and efficacy of VRC01 broadly neutralising antibodies in adults with acutely treated HIV (RV397): a phase 2, randomised, double-blind, placebo-controlled trial.
Crowell TA, Colby DJ, Pinyakorn S, Sacdalan C, Pagliuzza A, Intasan J, Benjapornpong K, Tangnaree K, Chomchey N, Kroon E, de Souza MS, Tovanabutra S, Rolland M, Eller MA, Paquin-Proulx D, Bolton DL, Tokarev A, Thomas R, Takata H, Trautmann L, Krebs SJ, Modjarrad K, McDermott AB, Bailer RT, Doria-Rose N, Patel B, Gorelick RJ, Fullmer BA, Schuetz A, Grandin PV, O'Connell RJ, Ledgerwood JE, Graham BS, Tressler R, Mascola JR, Chomont N, Michael NL, Robb ML, Phanuphak N, Ananworanich J; RV397 Study Group. Crowell TA, et al. Among authors: trautmann l. Lancet HIV. 2019 May;6(5):e297-e306. doi: 10.1016/S2352-3018(19)30053-0. Epub 2019 Apr 15. Lancet HIV. 2019. PMID: 31000477 Free PMC article. Clinical Trial.
HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation.
Chomont N, El-Far M, Ancuta P, Trautmann L, Procopio FA, Yassine-Diab B, Boucher G, Boulassel MR, Ghattas G, Brenchley JM, Schacker TW, Hill BJ, Douek DC, Routy JP, Haddad EK, Sékaly RP. Chomont N, et al. Among authors: trautmann l. Nat Med. 2009 Aug;15(8):893-900. doi: 10.1038/nm.1972. Epub 2009 Jun 21. Nat Med. 2009. PMID: 19543283 Free PMC article. Clinical Trial.
Reversible Reprogramming of Circulating Memory T Follicular Helper Cell Function during Chronic HIV Infection.
Cubas R, van Grevenynghe J, Wills S, Kardava L, Santich BH, Buckner CM, Muir R, Tardif V, Nichols C, Procopio F, He Z, Metcalf T, Ghneim K, Locci M, Ancuta P, Routy JP, Trautmann L, Li Y, McDermott AB, Koup RA, Petrovas C, Migueles SA, Connors M, Tomaras GD, Moir S, Crotty S, Haddad EK. Cubas R, et al. Among authors: trautmann l. J Immunol. 2015 Dec 15;195(12):5625-36. doi: 10.4049/jimmunol.1501524. Epub 2015 Nov 6. J Immunol. 2015. PMID: 26546609 Free PMC article.
Kill: boosting HIV-specific immune responses.
Trautmann L. Trautmann L. Curr Opin HIV AIDS. 2016 Jul;11(4):409-16. doi: 10.1097/COH.0000000000000286. Curr Opin HIV AIDS. 2016. PMID: 27054280 Free PMC article. Review.
Altered Memory Circulating T Follicular Helper-B Cell Interaction in Early Acute HIV Infection.
Muir R, Metcalf T, Tardif V, Takata H, Phanuphak N, Kroon E, Colby DJ, Trichavaroj R, Valcour V, Robb ML, Michael NL, Ananworanich J, Trautmann L, Haddad EK; RV254/SEARCH010 RV304/SEARCH 013 Study Groups. Muir R, et al. Among authors: trautmann l. PLoS Pathog. 2016 Jul 27;12(7):e1005777. doi: 10.1371/journal.ppat.1005777. eCollection 2016 Jul. PLoS Pathog. 2016. PMID: 27463374 Free PMC article.
High Number of Activated CD8+ T Cells Targeting HIV Antigens Are Present in Cerebrospinal Fluid in Acute HIV Infection.
Kessing CF, Spudich S, Valcour V, Cartwright P, Chalermchai T, Fletcher JL, Takata H, Nichols C, Josey BJ, Slike B, Krebs SJ, Sailsuta N, Lerdlum S, Jagodzinski L, Tipsuk S, Suttichom D, Rattanamanee S, Zetterberg H, Hellmuth J, Phanuphak N, Robb ML, Michael NL, Ananworanich J, Trautmann L. Kessing CF, et al. Among authors: trautmann l. J Acquir Immune Defic Syndr. 2017 May 1;75(1):108-117. doi: 10.1097/QAI.0000000000001301. J Acquir Immune Defic Syndr. 2017. PMID: 28177966 Free PMC article.
80 results