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54 results

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Page 1
KIT oncogene inhibition drives intratumoral macrophage M2 polarization.
Cavnar MJ, Zeng S, Kim TS, Sorenson EC, Ocuin LM, Balachandran VP, Seifert AM, Greer JB, Popow R, Crawley MH, Cohen NA, Green BL, Rossi F, Besmer P, Antonescu CR, DeMatteo RP. Cavnar MJ, et al. Among authors: seifert am. J Exp Med. 2013 Dec 16;210(13):2873-86. doi: 10.1084/jem.20130875. Epub 2013 Dec 9. J Exp Med. 2013. PMID: 24323358 Free PMC article.
Increased KIT inhibition enhances therapeutic efficacy in gastrointestinal stromal tumor.
Kim TS, Cavnar MJ, Cohen NA, Sorenson EC, Greer JB, Seifert AM, Crawley MH, Green BL, Popow R, Pillarsetty N, Veach DR, Ku AT, Rossi F, Besmer P, Antonescu CR, Zeng S, Dematteo RP. Kim TS, et al. Among authors: seifert am. Clin Cancer Res. 2014 May 1;20(9):2350-62. doi: 10.1158/1078-0432.CCR-13-3033. Epub 2014 Feb 28. Clin Cancer Res. 2014. PMID: 24583793 Free PMC article.
Pharmacological Inhibition of KIT Activates MET Signaling in Gastrointestinal Stromal Tumors.
Cohen NA, Zeng S, Seifert AM, Kim TS, Sorenson EC, Greer JB, Beckman MJ, Santamaria-Barria JA, Crawley MH, Green BL, Rossi F, Besmer P, Antonescu CR, DeMatteo RP. Cohen NA, et al. Among authors: seifert am. Cancer Res. 2015 May 15;75(10):2061-70. doi: 10.1158/0008-5472.CAN-14-2564. Epub 2015 Apr 2. Cancer Res. 2015. PMID: 25836719 Free PMC article.
Genome and transcriptome profiling of fibrolamellar hepatocellular carcinoma demonstrates p53 and IGF2BP1 dysregulation.
Sorenson EC, Khanin R, Bamboat ZM, Cavnar MJ, Kim TS, Sadot E, Zeng S, Greer JB, Seifert AM, Cohen NA, Crawley MH, Green BL, Klimstra DS, DeMatteo RP. Sorenson EC, et al. Among authors: seifert am. PLoS One. 2017 May 9;12(5):e0176562. doi: 10.1371/journal.pone.0176562. eCollection 2017. PLoS One. 2017. PMID: 28486549 Free PMC article.
Wnt/β-catenin Signaling Contributes to Tumor Malignancy and Is Targetable in Gastrointestinal Stromal Tumor.
Zeng S, Seifert AM, Zhang JQ, Cavnar MJ, Kim TS, Balachandran VP, Santamaria-Barria JA, Cohen NA, Beckman MJ, Medina BD, Rossi F, Crawley MH, Loo JK, Maltbaek JH, Besmer P, Antonescu CR, DeMatteo RP. Zeng S, et al. Among authors: seifert am. Mol Cancer Ther. 2017 Sep;16(9):1954-1966. doi: 10.1158/1535-7163.MCT-17-0139. Epub 2017 Jun 13. Mol Cancer Ther. 2017. PMID: 28611108 Free PMC article.
ETV4 collaborates with Wnt/β-catenin signaling to alter cell cycle activity and promote tumor aggressiveness in gastrointestinal stromal tumor.
Zeng S, Seifert AM, Zhang JQ, Kim TS, Bowler TG, Cavnar MJ, Medina BD, Vitiello GA, Rossi F, Loo JK, Param NJ, DeMatteo RP. Zeng S, et al. Among authors: seifert am. Oncotarget. 2017 Dec 11;8(69):114195-114209. doi: 10.18632/oncotarget.23173. eCollection 2017 Dec 26. Oncotarget. 2017. PMID: 29371979 Free PMC article.
Macrophages and CD8+ T Cells Mediate the Antitumor Efficacy of Combined CD40 Ligation and Imatinib Therapy in Gastrointestinal Stromal Tumors.
Zhang JQ, Zeng S, Vitiello GA, Seifert AM, Medina BD, Beckman MJ, Loo JK, Santamaria-Barria J, Maltbaek JH, Param NJ, Moral JA, Zhao JN, Balachandran V, Rossi F, Antonescu CR, DeMatteo RP. Zhang JQ, et al. Among authors: seifert am. Cancer Immunol Res. 2018 Apr;6(4):434-447. doi: 10.1158/2326-6066.CIR-17-0345. Epub 2018 Feb 21. Cancer Immunol Res. 2018. PMID: 29467128 Free PMC article.
Csf1r or Mer inhibition delays liver regeneration via suppression of Kupffer cells.
Santamaria-Barria JA, Zeng S, Greer JB, Beckman MJ, Seifert AM, Cohen NA, Zhang JQ, Crawley MH, Green BL, Loo JK, Maltbaek JH, DeMatteo RP. Santamaria-Barria JA, et al. Among authors: seifert am. PLoS One. 2019 May 1;14(5):e0216275. doi: 10.1371/journal.pone.0216275. eCollection 2019. PLoS One. 2019. PMID: 31042769 Free PMC article.
54 results