Laine RF - Search Results

1

Intrinsically aggregation-prone proteins form amyloid-like aggregates and contribute to tissue aging in Caenorhabditis elegans.

Huang C, Wagner-Valladolid S, Stephens AD, Jung R, Poudel C, Sinnige T, Lechler MC, Schlörit N, Lu M, Laine RF, Michel CH, Vendruscolo M, Kaminski CF, Kaminski Schierle GS, David DC. Huang C, et al. Among authors: laine rf. Elife. 2019 May 3;8:e43059. doi: 10.7554/eLife.43059. Elife. 2019. PMID: 31050339 Free PMC article.

2

Fast Fluorescence Lifetime Imaging Reveals the Aggregation Processes of α-Synuclein and Polyglutamine in Aging Caenorhabditis elegans.

Laine RF, Sinnige T, Ma KY, Haack AJ, Poudel C, Gaida P, Curry N, Perni M, Nollen EAA, Dobson CM, Vendruscolo M, Kaminski Schierle GS, Kaminski CF. Laine RF, et al. ACS Chem Biol. 2019 Jul 19;14(7):1628-1636. doi: 10.1021/acschembio.9b00354. Epub 2019 Jun 27. ACS Chem Biol. 2019. PMID: 31246415 Free PMC article.

3

Heparin acts as a structural component of β-endorphin amyloid fibrils rather than a simple aggregation promoter.

Nespovitaya N, Mahou P, Laine RF, Schierle GSK, Kaminski CF. Nespovitaya N, et al. Among authors: laine rf. Chem Commun (Camb). 2017 Jan 19;53(7):1273-1276. doi: 10.1039/c6cc09770g. Chem Commun (Camb). 2017. PMID: 28067354 Free PMC article.

4

Nanoscopic insights into seeding mechanisms and toxicity of α-synuclein species in neurons.

Pinotsi D, Michel CH, Buell AK, Laine RF, Mahou P, Dobson CM, Kaminski CF, Kaminski Schierle GS. Pinotsi D, et al. Among authors: laine rf. Proc Natl Acad Sci U S A. 2016 Apr 5;113(14):3815-9. doi: 10.1073/pnas.1516546113. Epub 2016 Mar 18. Proc Natl Acad Sci U S A. 2016. PMID: 26993805 Free PMC article.

5

Structured illumination microscopy combined with machine learning enables the high throughput analysis and classification of virus structure.

Laine RF, Goodfellow G, Young LJ, Travers J, Carroll D, Dibben O, Bright H, Kaminski CF. Laine RF, et al. Elife. 2018 Dec 13;7:e40183. doi: 10.7554/eLife.40183. Elife. 2018. PMID: 30543181 Free PMC article.

6

A method for the fast and photon-efficient analysis of time-domain fluorescence lifetime image data over large dynamic ranges.

Laine RF, Poudel C, Kaminski CF. Laine RF, et al. J Microsc. 2022 Sep;287(3):138-147. doi: 10.1111/jmi.13128. Epub 2022 Jun 23. J Microsc. 2022. PMID: 35676768 Free PMC article.

7

Comparative Studies in the A30P and A53T α-Synuclein C. elegans Strains to Investigate the Molecular Origins of Parkinson's Disease.

Perni M, van der Goot A, Limbocker R, van Ham TJ, Aprile FA, Xu CK, Flagmeier P, Thijssen K, Sormanni P, Fusco G, Chen SW, Challa PK, Kirkegaard JB, Laine RF, Ma KY, Müller MBD, Sinnige T, Kumita JR, Cohen SIA, Seinstra R, Kaminski Schierle GS, Kaminski CF, Barbut D, De Simone A, Knowles TPJ, Zasloff M, Nollen EAA, Vendruscolo M, Dobson CM. Perni M, et al. Among authors: laine rf. Front Cell Dev Biol. 2021 Mar 22;9:552549. doi: 10.3389/fcell.2021.552549. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 33829010 Free PMC article.

8

From single-molecule spectroscopy to super-resolution imaging of the neuron: a review.

Laine RF, Kaminski Schierle GS, van de Linde S, Kaminski CF. Laine RF, et al. Methods Appl Fluoresc. 2016 Jun 27;4(2):022004. doi: 10.1088/2050-6120/4/2/022004. Methods Appl Fluoresc. 2016. PMID: 28809165 Free PMC article. Review.

9

C-terminal calcium binding of α-synuclein modulates synaptic vesicle interaction.

Lautenschläger J, Stephens AD, Fusco G, Ströhl F, Curry N, Zacharopoulou M, Michel CH, Laine R, Nespovitaya N, Fantham M, Pinotsi D, Zago W, Fraser P, Tandon A, St George-Hyslop P, Rees E, Phillips JJ, De Simone A, Kaminski CF, Schierle GSK. Lautenschläger J, et al. Nat Commun. 2018 Feb 19;9(1):712. doi: 10.1038/s41467-018-03111-4. Nat Commun. 2018. PMID: 29459792 Free PMC article.

10

HSV-1 Glycoproteins Are Delivered to Virus Assembly Sites Through Dynamin-Dependent Endocytosis.

Albecka A, Laine RF, Janssen AF, Kaminski CF, Crump CM. Albecka A, et al. Among authors: laine rf. Traffic. 2016 Jan;17(1):21-39. doi: 10.1111/tra.12340. Epub 2015 Nov 6. Traffic. 2016. PMID: 26459807 Free PMC article.

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