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Design and Discovery of N-(3-(2-(2-Hydroxyethoxy)-6-morpholinopyridin-4-yl)-4-methylphenyl)-2-(trifluoromethyl)isonicotinamide, a Selective, Efficacious, and Well-Tolerated RAF Inhibitor Targeting RAS Mutant Cancers: The Path to the Clinic.
Ramurthy S, Taft BR, Aversa RJ, Barsanti PA, Burger MT, Lou Y, Nishiguchi GA, Rico A, Setti L, Smith A, Subramanian S, Tamez V, Tanner H, Wan L, Hu C, Appleton BA, Mamo M, Tandeske L, Tellew JE, Huang S, Yue Q, Chaudhary A, Tian H, Iyer R, Hassan AQ, Mathews Griner LA, La Bonte LR, Cooke VG, Van Abbema A, Merritt H, Gampa K, Feng F, Yuan J, Mishina Y, Wang Y, Haling JR, Vaziri S, Hekmat-Nejad M, Polyakov V, Zang R, Sethuraman V, Amiri P, Singh M, Sellers WR, Lees E, Shao W, Dillon MP, Stuart DD. Ramurthy S, et al. Among authors: tanner h. J Med Chem. 2020 Mar 12;63(5):2013-2027. doi: 10.1021/acs.jmedchem.9b00161. Epub 2019 May 16. J Med Chem. 2020. PMID: 31059256
Design and Discovery of N-(2-Methyl-5'-morpholino-6'-((tetrahydro-2H-pyran-4-yl)oxy)-[3,3'-bipyridin]-5-yl)-3-(trifluoromethyl)benzamide (RAF709): A Potent, Selective, and Efficacious RAF Inhibitor Targeting RAS Mutant Cancers.
Nishiguchi GA, Rico A, Tanner H, Aversa RJ, Taft BR, Subramanian S, Setti L, Burger MT, Wan L, Tamez V, Smith A, Lou Y, Barsanti PA, Appleton BA, Mamo M, Tandeske L, Dix I, Tellew JE, Huang S, Mathews Griner LA, Cooke VG, Van Abbema A, Merritt H, Ma S, Gampa K, Feng F, Yuan J, Wang Y, Haling JR, Vaziri S, Hekmat-Nejad M, Jansen JM, Polyakov V, Zang R, Sethuraman V, Amiri P, Singh M, Lees E, Shao W, Stuart DD, Dillon MP, Ramurthy S. Nishiguchi GA, et al. Among authors: tanner h. J Med Chem. 2017 Jun 22;60(12):4869-4881. doi: 10.1021/acs.jmedchem.6b01862. Epub 2017 Jun 8. J Med Chem. 2017. PMID: 28557458
Comparison of the Feasibility and Safety of a Deep Sedation Protocol for Pulmonary Vein Isolation With Pulsed Field Ablation, Cryoballoon Ablation, and Radiofrequency Ablation.
Galuszka OM, Kueffer T, Madaffari A, Kozhuharov N, Thalmann G, Servatius H, Haeberlin A, Noti F, Tanner H, Roten L, Reichlin T. Galuszka OM, et al. Among authors: tanner h. J Am Heart Assoc. 2024 Jun 4;13(11):e033210. doi: 10.1161/JAHA.123.033210. Epub 2024 May 31. J Am Heart Assoc. 2024. PMID: 38818944 Free article. No abstract available.
A summary of the 2023 Society of Obstetric Medicine of Australia and New Zealand (SOMANZ) hypertension in pregnancy guideline.
Shanmugalingam R, Barrett HL, Beech A, Bowyer L, Crozier T, Davidson A, Dekker Nitert M, Doyle K, Grzeskowiak L, Hall N, Cheikh Hassan HI, Hennessy A, Henry A, Langsford D, Lee VW, Munn Z, Peek MJ, Said JM, Tanner H, Taylor R, Ward M, Waugh J, Yen LL, Medcalf E, Bell KJ, Ackermann D, Turner R, Makris A. Shanmugalingam R, et al. Among authors: tanner h. Med J Aust. 2024 May 19. doi: 10.5694/mja2.52312. Online ahead of print. Med J Aust. 2024. PMID: 38763516
PolarX vs Arctic Front for Cryoballoon Ablation of Paroxysmal AF: The Randomized COMPARE CRYO Study.
Reichlin T, Kueffer T, Knecht S, Madaffari A, Badertscher P, Maurhofer J, Krisai P, Jufer C, Asatryan B, Heg D, Servatius H, Tanner H, Kühne M, Roten L, Sticherling C. Reichlin T, et al. Among authors: tanner h. JACC Clin Electrophysiol. 2024 Apr 30:S2405-500X(24)00255-X. doi: 10.1016/j.jacep.2024.03.021. Online ahead of print. JACC Clin Electrophysiol. 2024. PMID: 38752963
231 results