Afek A - Search Results

1

QBiC-Pred: quantitative predictions of transcription factor binding changes due to sequence variants.

Martin V, Zhao J, Afek A, Mielko Z, Gordân R. Martin V, et al. Among authors: afek a. Nucleic Acids Res. 2019 Jul 2;47(W1):W127-W135. doi: 10.1093/nar/gkz363. Nucleic Acids Res. 2019. PMID: 31114870 Free PMC article.

2

Protein-DNA binding in the absence of specific base-pair recognition.

Afek A, Schipper JL, Horton J, Gordân R, Lukatsky DB. Afek A, et al. Proc Natl Acad Sci U S A. 2014 Dec 2;111(48):17140-5. doi: 10.1073/pnas.1410569111. Epub 2014 Oct 13. Proc Natl Acad Sci U S A. 2014. PMID: 25313048 Free PMC article.

3

Nonconsensus Protein Binding to Repetitive DNA Sequence Elements Significantly Affects Eukaryotic Genomes.

Afek A, Cohen H, Barber-Zucker S, Gordân R, Lukatsky DB. Afek A, et al. PLoS Comput Biol. 2015 Aug 18;11(8):e1004429. doi: 10.1371/journal.pcbi.1004429. eCollection 2015 Aug. PLoS Comput Biol. 2015. PMID: 26285121 Free PMC article.

4

Toward deciphering the mechanistic role of variations in the Rep1 repeat site in the transcription regulation of SNCA gene.

Afek A, Tagliafierro L, Glenn OC, Lukatsky DB, Gordan R, Chiba-Falek O. Afek A, et al. Neurogenetics. 2018 Aug;19(3):135-144. doi: 10.1007/s10048-018-0546-8. Epub 2018 May 5. Neurogenetics. 2018. PMID: 29730780 Free PMC article.

5

DNA Sequence Context Controls the Binding and Processivity of the T7 DNA Primase.

Afek A, Ilic S, Horton J, Lukatsky DB, Gordan R, Akabayov B. Afek A, et al. iScience. 2018 Apr 27;2:141-147. doi: 10.1016/j.isci.2018.03.019. Epub 2018 Mar 27. iScience. 2018. PMID: 30428370 Free PMC article.

6

Unexpected implications of STAT3 acetylation revealed by genetic encoding of acetyl-lysine.

Belo Y, Mielko Z, Nudelman H, Afek A, Ben-David O, Shahar A, Zarivach R, Gordan R, Arbely E. Belo Y, et al. Among authors: afek a. Biochim Biophys Acta Gen Subj. 2019 Sep;1863(9):1343-1350. doi: 10.1016/j.bbagen.2019.05.019. Epub 2019 Jun 3. Biochim Biophys Acta Gen Subj. 2019. PMID: 31170499 Free PMC article.

7

DNA Sequence Recognition by DNA Primase Using High-Throughput Primase Profiling.

Ilic S, Cohen S, Afek A, Gordan R, Lukatsky DB, Akabayov B. Ilic S, et al. Among authors: afek a. J Vis Exp. 2019 Oct 8;(152). doi: 10.3791/59737. J Vis Exp. 2019. PMID: 31657797

8

DNA mismatches reveal conformational penalties in protein-DNA recognition.

Afek A, Shi H, Rangadurai A, Sahay H, Senitzki A, Xhani S, Fang M, Salinas R, Mielko Z, Pufall MA, Poon GMK, Haran TE, Schumacher MA, Al-Hashimi HM, Gordân R. Afek A, et al. Nature. 2020 Nov;587(7833):291-296. doi: 10.1038/s41586-020-2843-2. Epub 2020 Oct 21. Nature. 2020. PMID: 33087930 Free PMC article.

9

UV irradiation remodels the specificity landscape of transcription factors.

Mielko Z, Zhang Y, Sahay H, Liu Y, Schaich MA, Schnable B, Morrison AM, Burdinski D, Adar S, Pufall M, Van Houten B, Gordân R, Afek A. Mielko Z, et al. Among authors: afek a. Proc Natl Acad Sci U S A. 2023 Mar 14;120(11):e2217422120. doi: 10.1073/pnas.2217422120. Epub 2023 Mar 8. Proc Natl Acad Sci U S A. 2023. PMID: 36888663 Free PMC article.

10

Short tandem repeats bind transcription factors to tune eukaryotic gene expression.

Horton CA, Alexandari AM, Hayes MGB, Marklund E, Schaepe JM, Aditham AK, Shah N, Suzuki PH, Shrikumar A, Afek A, Greenleaf WJ, Gordân R, Zeitlinger J, Kundaje A, Fordyce PM. Horton CA, et al. Among authors: afek a. Science. 2023 Sep 22;381(6664):eadd1250. doi: 10.1126/science.add1250. Epub 2023 Sep 22. Science. 2023. PMID: 37733848

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