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A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure.
Sung YJ, de Las Fuentes L, Winkler TW, Chasman DI, Bentley AR, Kraja AT, Ntalla I, Warren HR, Guo X, Schwander K, Manning AK, Brown MR, Aschard H, Feitosa MF, Franceschini N, Lu Y, Cheng CY, Sim X, Vojinovic D, Marten J, Musani SK, Kilpeläinen TO, Richard MA, Aslibekyan S, Bartz TM, Dorajoo R, Li C, Liu Y, Rankinen T, Smith AV, Tajuddin SM, Tayo BO, Zhao W, Zhou Y, Matoba N, Sofer T, Alver M, Amini M, Boissel M, Chai JF, Chen X, Divers J, Gandin I, Gao C, Giulianini F, Goel A, Harris SE, Hartwig FP, He M, Horimoto ARVR, Hsu FC, Jackson AU, Kammerer CM, Kasturiratne A, Komulainen P, Kühnel B, Leander K, Lee WJ, Lin KH, Luan J, Lyytikäinen LP, McKenzie CA, Nelson CP, Noordam R, Scott RA, Sheu WHH, Stančáková A, Takeuchi F, van der Most PJ, Varga TV, Waken RJ, Wang H, Wang Y, Ware EB, Weiss S, Wen W, Yanek LR, Zhang W, Zhao JH, Afaq S, Alfred T, Amin N, Arking DE, Aung T, Barr RG, Bielak LF, Boerwinkle E, Bottinger EP, Braund PS, Brody JA, Broeckel U, Cade B, Campbell A, Canouil M, Chakravarti A, Cocca M, Collins FS, Connell JM, de Mutsert R, de Silva HJ, Dörr M, Duan Q, Eaton CB, Ehret G, Evangelou E, Faul JD, Forouhi NG, Franco OH, Friedlander Y, Gao H, Gigante B, Gu CC, Gup… See abstract for full author list ➔ Sung YJ, et al. Among authors: aslibekyan s. Hum Mol Genet. 2019 Aug 1;28(15):2615-2633. doi: 10.1093/hmg/ddz070. Hum Mol Genet. 2019. PMID: 31127295 Free PMC article.
Variants identified in a GWAS meta-analysis for blood lipids are associated with the lipid response to fenofibrate.
Aslibekyan S, Goodarzi MO, Frazier-Wood AC, Yan X, Irvin MR, Kim E, Tiwari HK, Guo X, Straka RJ, Taylor KD, Tsai MY, Hopkins PN, Korenman SG, Borecki IB, Chen YD, Ordovas JM, Rotter JI, Arnett DK. Aslibekyan S, et al. PLoS One. 2012;7(10):e48663. doi: 10.1371/journal.pone.0048663. Epub 2012 Oct 31. PLoS One. 2012. PMID: 23119086 Free PMC article.
Preliminary evidence of genetic determinants of adiponectin response to fenofibrate in the Genetics of Lipid Lowering Drugs and Diet Network.
Aslibekyan S, An P, Frazier-Wood AC, Kabagambe EK, Irvin MR, Straka RJ, Tiwari HK, Tsai MY, Hopkins PN, Borecki IB, Ordovas JM, Arnett DK. Aslibekyan S, et al. Nutr Metab Cardiovasc Dis. 2013 Oct;23(10):987-94. doi: 10.1016/j.numecd.2012.07.010. Epub 2012 Nov 11. Nutr Metab Cardiovasc Dis. 2013. PMID: 23149075 Free PMC article.
Genetic variants associated with VLDL, LDL and HDL particle size differ with race/ethnicity.
Frazier-Wood AC, Manichaikul A, Aslibekyan S, Borecki IB, Goff DC, Hopkins PN, Lai CQ, Ordovas JM, Post WS, Rich SS, Sale MM, Siscovick D, Straka RJ, Tiwari HK, Tsai MY, Rotter JI, Arnett DK. Frazier-Wood AC, et al. Among authors: aslibekyan s. Hum Genet. 2013 Apr;132(4):405-13. doi: 10.1007/s00439-012-1256-1. Epub 2012 Dec 22. Hum Genet. 2013. PMID: 23263444 Free PMC article. Clinical Trial.
SNPs located at CpG sites modulate genome-epigenome interaction.
Zhi D, Aslibekyan S, Irvin MR, Claas SA, Borecki IB, Ordovas JM, Absher DM, Arnett DK. Zhi D, et al. Among authors: aslibekyan s. Epigenetics. 2013 Aug;8(8):802-6. doi: 10.4161/epi.25501. Epub 2013 Jun 28. Epigenetics. 2013. PMID: 23811543 Free PMC article.
200 results