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Genetic analyses led to the discovery of a super-active mutant of the RNA polymerase I.
Darrière T, Pilsl M, Sarthou MK, Chauvier A, Genty T, Audibert S, Dez C, Léger-Silvestre I, Normand C, Henras AK, Kwapisz M, Calvo O, Fernández-Tornero C, Tschochner H, Gadal O. Darrière T, et al. Among authors: calvo o. PLoS Genet. 2019 May 28;15(5):e1008157. doi: 10.1371/journal.pgen.1008157. eCollection 2019 May. PLoS Genet. 2019. PMID: 31136569 Free PMC article.
Sub1 contacts the RNA polymerase II stalk to modulate mRNA synthesis.
Garavís M, González-Polo N, Allepuz-Fuster P, Louro JA, Fernández-Tornero C, Calvo O. Garavís M, et al. Among authors: calvo o. Nucleic Acids Res. 2017 Mar 17;45(5):2458-2471. doi: 10.1093/nar/gkw1206. Nucleic Acids Res. 2017. PMID: 27924005 Free PMC article.
Structural basis of RNA polymerase I stalling at UV light-induced DNA damage.
Sanz-Murillo M, Xu J, Belogurov GA, Calvo O, Gil-Carton D, Moreno-Morcillo M, Wang D, Fernández-Tornero C. Sanz-Murillo M, et al. Among authors: calvo o. Proc Natl Acad Sci U S A. 2018 Sep 4;115(36):8972-8977. doi: 10.1073/pnas.1802626115. Epub 2018 Aug 20. Proc Natl Acad Sci U S A. 2018. PMID: 30127008 Free PMC article.
51 results