Rode A - Search Results

1

Defining the Contribution of CYP1A1 and CYP1A2 to Drug Metabolism Using Humanized CYP1A1/1A2 and Cyp1a1/Cyp1a2 Knockout Mice.

Kapelyukh Y, Henderson CJ, Scheer N, Rode A, Wolf CR. Kapelyukh Y, et al. Among authors: rode a. Drug Metab Dispos. 2019 Aug;47(8):907-918. doi: 10.1124/dmd.119.087718. Epub 2019 May 30. Drug Metab Dispos. 2019. PMID: 31147315 Free PMC article.

2

An Extensively Humanized Mouse Model to Predict Pathways of Drug Disposition and Drug/Drug Interactions, and to Facilitate Design of Clinical Trials.

Henderson CJ, Kapelyukh Y, Scheer N, Rode A, McLaren AW, MacLeod AK, Lin D, Wright J, Stanley LA, Wolf CR. Henderson CJ, et al. Among authors: rode a. Drug Metab Dispos. 2019 Jun;47(6):601-615. doi: 10.1124/dmd.119.086397. Epub 2019 Mar 25. Drug Metab Dispos. 2019. PMID: 30910785 Free PMC article.

3

Deletion of 30 murine cytochrome p450 genes results in viable mice with compromised drug metabolism.

Scheer N, McLaughlin LA, Rode A, Macleod AK, Henderson CJ, Wolf CR. Scheer N, et al. Among authors: rode a. Drug Metab Dispos. 2014 Jun;42(6):1022-30. doi: 10.1124/dmd.114.057885. Epub 2014 Mar 26. Drug Metab Dispos. 2014. PMID: 24671958

4

Defining Human Pathways of Drug Metabolism In Vivo through the Development of a Multiple Humanized Mouse Model.

Scheer N, Kapelyukh Y, Rode A, Oswald S, Busch D, McLaughlin LA, Lin D, Henderson CJ, Wolf CR. Scheer N, et al. Among authors: rode a. Drug Metab Dispos. 2015 Nov;43(11):1679-90. doi: 10.1124/dmd.115.065656. Epub 2015 Aug 11. Drug Metab Dispos. 2015. PMID: 26265742

5

In vivo responses of the human and murine pregnane X receptor to dexamethasone in mice.

Scheer N, Ross J, Kapelyukh Y, Rode A, Wolf CR. Scheer N, et al. Among authors: rode a. Drug Metab Dispos. 2010 Jul;38(7):1046-53. doi: 10.1124/dmd.109.031872. Epub 2010 Mar 30. Drug Metab Dispos. 2010. PMID: 20354104

6

Modeling human cytochrome P450 2D6 metabolism and drug-drug interaction by a novel panel of knockout and humanized mouse lines.

Scheer N, Kapelyukh Y, McEwan J, Beuger V, Stanley LA, Rode A, Wolf CR. Scheer N, et al. Among authors: rode a. Mol Pharmacol. 2012 Jan;81(1):63-72. doi: 10.1124/mol.111.075192. Epub 2011 Oct 11. Mol Pharmacol. 2012. PMID: 21989258

7

Generation and characterization of novel cytochrome P450 Cyp2c gene cluster knockout and CYP2C9 humanized mouse lines.

Scheer N, Kapelyukh Y, Chatham L, Rode A, Buechel S, Wolf CR. Scheer N, et al. Among authors: rode a. Mol Pharmacol. 2012 Dec;82(6):1022-9. doi: 10.1124/mol.112.080036. Epub 2012 Aug 23. Mol Pharmacol. 2012. PMID: 22918969

8

Human constitutive androstane receptor (CAR) and pregnane X receptor (PXR) support the hypertrophic but not the hyperplastic response to the murine nongenotoxic hepatocarcinogens phenobarbital and chlordane in vivo.

Ross J, Plummer SM, Rode A, Scheer N, Bower CC, Vogel O, Henderson CJ, Wolf CR, Elcombe CR. Ross J, et al. Among authors: rode a. Toxicol Sci. 2010 Aug;116(2):452-66. doi: 10.1093/toxsci/kfq118. Epub 2010 Apr 19. Toxicol Sci. 2010. PMID: 20403969

9

Quantitative prediction of human pregnane X receptor and cytochrome P450 3A4 mediated drug-drug interaction in a novel multiple humanized mouse line.

Hasegawa M, Kapelyukh Y, Tahara H, Seibler J, Rode A, Krueger S, Lee DN, Wolf CR, Scheer N. Hasegawa M, et al. Among authors: rode a. Mol Pharmacol. 2011 Sep;80(3):518-28. doi: 10.1124/mol.111.071845. Epub 2011 May 31. Mol Pharmacol. 2011. PMID: 21628639

10

Evaluation of organic anion transporting polypeptide 1B1 and 1B3 humanized mice as a translational model to study the pharmacokinetics of statins.

Salphati L, Chu X, Chen L, Prasad B, Dallas S, Evers R, Mamaril-Fishman D, Geier EG, Kehler J, Kunta J, Mezler M, Laplanche L, Pang J, Rode A, Soars MG, Unadkat JD, van Waterschoot RA, Yabut J, Schinkel AH, Scheer N. Salphati L, et al. Among authors: rode a. Drug Metab Dispos. 2014 Aug;42(8):1301-13. doi: 10.1124/dmd.114.057976. Epub 2014 May 22. Drug Metab Dispos. 2014. PMID: 24855184

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

318 results

Search Page