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The giant titin: how to evaluate its role in cardiomyopathies.
Azad A, Poloni G, Sontayananon N, Jiang H, Gehmlich K. Azad A, et al. Among authors: jiang h. J Muscle Res Cell Motil. 2019 Jun;40(2):159-167. doi: 10.1007/s10974-019-09518-w. Epub 2019 May 30. J Muscle Res Cell Motil. 2019. PMID: 31147888 Free PMC article. Review.
HspB1 phosphorylation regulates its intramolecular dynamics and mechanosensitive molecular chaperone interaction with filamin C.
Collier MP, Alderson TR, de Villiers CP, Nicholls D, Gastall HY, Allison TM, Degiacomi MT, Jiang H, Mlynek G, Fürst DO, van der Ven PFM, Djinovic-Carugo K, Baldwin AJ, Watkins H, Gehmlich K, Benesch JLP. Collier MP, et al. Among authors: jiang h. Sci Adv. 2019 May 22;5(5):eaav8421. doi: 10.1126/sciadv.aav8421. eCollection 2019 May. Sci Adv. 2019. PMID: 31131323 Free PMC article.
Functional analysis of a gene-edited mouse model to gain insights into the disease mechanisms of a titin missense variant.
Jiang H, Hooper C, Kelly M, Steeples V, Simon JN, Beglov J, Azad AJ, Leinhos L, Bennett P, Ehler E, Kalisch-Smith JI, Sparrow DB, Fischer R, Heilig R, Isackson H, Ehsan M, Patone G, Huebner N, Davies B, Watkins H, Gehmlich K. Jiang H, et al. Basic Res Cardiol. 2021 Feb 26;116(1):14. doi: 10.1007/s00395-021-00853-z. Basic Res Cardiol. 2021. PMID: 33637999 Free PMC article.
Insights into the Role of a Cardiomyopathy-Causing Genetic Variant in ACTN2.
Broadway-Stringer S, Jiang H, Wadmore K, Hooper C, Douglas G, Steeples V, Azad AJ, Singer E, Reyat JS, Galatik F, Ehler E, Bennett P, Kalisch-Smith JI, Sparrow DB, Davies B, Djinovic-Carugo K, Gautel M, Watkins H, Gehmlich K. Broadway-Stringer S, et al. Among authors: jiang h. Cells. 2023 Feb 24;12(5):721. doi: 10.3390/cells12050721. Cells. 2023. PMID: 36899856 Free PMC article.
Cardiac Hypertrophy Is Inhibited by a Local Pool of cAMP Regulated by Phosphodiesterase 2.
Zoccarato A, Surdo NC, Aronsen JM, Fields LA, Mancuso L, Dodoni G, Stangherlin A, Livie C, Jiang H, Sin YY, Gesellchen F, Terrin A, Baillie GS, Nicklin SA, Graham D, Szabo-Fresnais N, Krall J, Vandeput F, Movsesian M, Furlan L, Corsetti V, Hamilton G, Lefkimmiatis K, Sjaastad I, Zaccolo M. Zoccarato A, et al. Among authors: jiang h. Circ Res. 2015 Sep 25;117(8):707-19. doi: 10.1161/CIRCRESAHA.114.305892. Epub 2015 Aug 4. Circ Res. 2015. PMID: 26243800 Free article.
A quick and innovative pipeline for producing chondrocyte-homing peptide-modified extracellular vesicles by three-dimensional dynamic culture of hADSCs spheroids to modulate the fate of remaining ear chondrocytes in the M1 macrophage-infiltrated microenvironment.
Chen J, Zhang E, Wan Y, Huang T, Wang Y, Jiang H. Chen J, et al. Among authors: jiang h. J Nanobiotechnology. 2024 May 30;22(1):300. doi: 10.1186/s12951-024-02567-5. J Nanobiotechnology. 2024. PMID: 38816719
De novo design of buttressed loops for sculpting protein functions.
Jiang H, Jude KM, Wu K, Fallas J, Ueda G, Brunette TJ, Hicks DR, Pyles H, Yang A, Carter L, Lamb M, Li X, Levine PM, Stewart L, Garcia KC, Baker D. Jiang H, et al. Nat Chem Biol. 2024 May 30. doi: 10.1038/s41589-024-01632-2. Online ahead of print. Nat Chem Biol. 2024. PMID: 38816644
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