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Discovery of O-glycans on atrial natriuretic peptide (ANP) that affect both its proteolytic degradation and potency at its cognate receptor.
Hansen LH, Madsen TD, Goth CK, Clausen H, Chen Y, Dzhoyashvili N, Iyer SR, Sangaralingham SJ, Burnett JC Jr, Rehfeld JF, Vakhrushev SY, Schjoldager KT, Goetze JP. Hansen LH, et al. Among authors: chen y. J Biol Chem. 2019 Aug 23;294(34):12567-12578. doi: 10.1074/jbc.RA119.008102. Epub 2019 Jun 11. J Biol Chem. 2019. PMID: 31186350 Free PMC article.
CRRL269: a novel designer and renal-enhancing pGC-A peptide activator.
Chen Y, Harty GJ, Huntley BK, Iyer SR, Heublein DM, Harders GE, Meems L, Pan S, Sangaralingham SJ, Ichiki T, Burnett JC Jr. Chen Y, et al. Am J Physiol Regul Integr Comp Physiol. 2018 Mar 1;314(3):R407-R414. doi: 10.1152/ajpregu.00286.2017. Epub 2017 Nov 29. Am J Physiol Regul Integr Comp Physiol. 2018. PMID: 29187381 Free PMC article.
Design, Synthesis, and Actions of an Innovative Bispecific Designer Peptide.
Meems LMG, Andersen IA, Pan S, Harty G, Chen Y, Zheng Y, Harders GE, Ichiki T, Heublein DM, Iyer SR, Sangaralingham SJ, McCormick DJ, Burnett JC Jr. Meems LMG, et al. Among authors: chen y. Hypertension. 2019 Apr;73(4):900-909. doi: 10.1161/HYPERTENSIONAHA.118.12012. Hypertension. 2019. PMID: 30798663 Free PMC article.
C-type natriuretic peptide: the heart's guardian angel.
Sangaralingham SJ, Chen Y, Burnett JC. Sangaralingham SJ, et al. Among authors: chen y. Eur Heart J. 2020 Mar 1;41(9):1021-1023. doi: 10.1093/eurheartj/ehz142. Eur Heart J. 2020. PMID: 30907411 Free PMC article. No abstract available.
CRRL269.
Chen Y, Harty GJ, Zheng Y, Iyer SR, Sugihara S, Sangaralingham SJ, Ichiki T, Grande JP, Lee HC, Wang X, Burnett JC Jr. Chen Y, et al. Circ Res. 2019 May 10;124(10):1462-1472. doi: 10.1161/CIRCRESAHA.118.314164. Circ Res. 2019. PMID: 30929579 Free PMC article.
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