Li X - Search Results

1

Site-Selective Antibody Functionalization via Orthogonally Reactive Arginine and Lysine Residues.

Hwang D, Nilchan N, Nanna AR, Li X, Cameron MD, Roush WR, Park H, Rader C. Hwang D, et al. Among authors: li x. Cell Chem Biol. 2019 Sep 19;26(9):1229-1239.e9. doi: 10.1016/j.chembiol.2019.05.010. Epub 2019 Jun 20. Cell Chem Biol. 2019. PMID: 31231031 Free PMC article.

2

Potential role of a quetiapine metabolite in quetiapine-induced neutropenia and agranulocytosis.

Li X, Cameron MD. Li X, et al. Chem Res Toxicol. 2012 May 21;25(5):1004-11. doi: 10.1021/tx2005635. Epub 2012 Apr 25. Chem Res Toxicol. 2012. PMID: 22506851

3

Bioactivation of the epidermal growth factor receptor inhibitor gefitinib: implications for pulmonary and hepatic toxicities.

Li X, Kamenecka TM, Cameron MD. Li X, et al. Chem Res Toxicol. 2009 Oct;22(10):1736-42. doi: 10.1021/tx900256y. Chem Res Toxicol. 2009. PMID: 19803472

4

Cytochrome P450-mediated bioactivation of the epidermal growth factor receptor inhibitor erlotinib to a reactive electrophile.

Li X, Kamenecka TM, Cameron MD. Li X, et al. Drug Metab Dispos. 2010 Jul;38(7):1238-45. doi: 10.1124/dmd.109.030361. Epub 2010 Apr 9. Drug Metab Dispos. 2010. PMID: 20382753 Free PMC article.

5

Imidazopyridines as selective CYP3A4 inhibitors.

Song X, Li X, Ruiz CH, Yin Y, Feng Y, Kamenecka TM, Cameron MD. Song X, et al. Among authors: li x. Bioorg Med Chem Lett. 2012 Feb 15;22(4):1611-4. doi: 10.1016/j.bmcl.2011.12.125. Epub 2012 Jan 4. Bioorg Med Chem Lett. 2012. PMID: 22264486 Free PMC article.

6

Discovery of a highly selective CYP3A4 inhibitor suitable for reaction phenotyping studies and differentiation of CYP3A4 and CYP3A5.

Li X, Song X, Kamenecka TM, Cameron MD. Li X, et al. Drug Metab Dispos. 2012 Sep;40(9):1803-9. doi: 10.1124/dmd.112.046144. Epub 2012 Jun 13. Drug Metab Dispos. 2012. PMID: 22696420 Free PMC article.

7

Characterization of dasatinib and its structural analogs as CYP3A4 mechanism-based inactivators and the proposed bioactivation pathways.

Li X, He Y, Ruiz CH, Koenig M, Cameron MD, Vojkovsky T. Li X, et al. Drug Metab Dispos. 2009 Jun;37(6):1242-50. doi: 10.1124/dmd.108.025932. Epub 2009 Mar 12. Drug Metab Dispos. 2009. PMID: 19282395 Free PMC article.

8

Characterization of T-5 N-oxide formation as the first highly selective measure of CYP3A5 activity.

Li X, Jeso V, Heyward S, Walker GS, Sharma R, Micalizio GC, Cameron MD. Li X, et al. Drug Metab Dispos. 2014 Mar;42(3):334-42. doi: 10.1124/dmd.113.054726. Epub 2013 Dec 11. Drug Metab Dispos. 2014. PMID: 24335391 Free PMC article.

9

Oxidative Metabolism as a Modulator of Kratom's Biological Actions.

Chakraborty S, Uprety R, Slocum ST, Irie T, Le Rouzic V, Li X, Wilson LL, Scouller B, Alder AF, Kruegel AC, Ansonoff M, Varadi A, Eans SO, Hunkele A, Allaoa A, Kalra S, Xu J, Pan YX, Pintar J, Kivell BM, Pasternak GW, Cameron MD, McLaughlin JP, Sames D, Majumdar S. Chakraborty S, et al. Among authors: li x. J Med Chem. 2021 Nov 25;64(22):16553-16572. doi: 10.1021/acs.jmedchem.1c01111. Epub 2021 Nov 16. J Med Chem. 2021. PMID: 34783240 Free PMC article.

10

Urine multi-index intelligent detection based on polymer/paper hybrid microfluidic biochip for hyperuricemia monitoring.

Wang C, Xue Q, Li H, Qi H, Li X. Wang C, et al. Among authors: li x. Anal Chim Acta. 2024 Jul 11;1312:342742. doi: 10.1016/j.aca.2024.342742. Epub 2024 May 21. Anal Chim Acta. 2024. PMID: 38834261

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