Placental epigenetic clocks: estimating gestational age using placental DNA methylation levels.
Lee Y, Choufani S, Weksberg R, Wilson SL, Yuan V, Burt A, Marsit C, Lu AT, Ritz B, Bohlin J, Gjessing HK, Harris JR, Magnus P, Binder AM, Robinson WP, Jugessur A, Horvath S.
Lee Y, et al. Among authors: horvath s.
Aging (Albany NY). 2019 Jun 24;11(12):4238-4253. doi: 10.18632/aging.102049.
Aging (Albany NY). 2019.
PMID: 31235674
Free PMC article.
We show that epigenetic clocks derived from cord blood or other tissues do not accurately estimate GA in placental samples. While fundamentally different from Horvath's pan-tissue epigenetic clock, placental clocks closely track fetal age during development and may …
We show that epigenetic clocks derived from cord blood or other tissues do not accurately estimate GA in placental samples. While fundamenta …