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Pathologic gene network rewiring implicates PPP1R3A as a central regulator in pressure overload heart failure.
Cordero P, Parikh VN, Chin ET, Erbilgin A, Gloudemans MJ, Shang C, Huang Y, Chang AC, Smith KS, Dewey F, Zaleta K, Morley M, Brandimarto J, Glazer N, Waggott D, Pavlovic A, Zhao M, Moravec CS, Tang WHW, Skreen J, Malloy C, Hannenhalli S, Li H, Ritter S, Li M, Bernstein D, Connolly A, Hakonarson H, Lusis AJ, Margulies KB, Depaoli-Roach AA, Montgomery SB, Wheeler MT, Cappola T, Ashley EA. Cordero P, et al. Among authors: connolly a. Nat Commun. 2019 Jun 24;10(1):2760. doi: 10.1038/s41467-019-10591-5. Nat Commun. 2019. PMID: 31235787 Free PMC article.
Network analysis of human in-stent restenosis.
Ashley EA, Ferrara R, King JY, Vailaya A, Kuchinsky A, He X, Byers B, Gerckens U, Oblin S, Tsalenko A, Soito A, Spin JM, Tabibiazar R, Connolly AJ, Simpson JB, Grube E, Quertermous T. Ashley EA, et al. Among authors: connolly aj. Circulation. 2006 Dec 12;114(24):2644-54. doi: 10.1161/CIRCULATIONAHA.106.637025. Epub 2006 Dec 4. Circulation. 2006. PMID: 17145989
Pathway analysis of coronary atherosclerosis.
King JY, Ferrara R, Tabibiazar R, Spin JM, Chen MM, Kuchinsky A, Vailaya A, Kincaid R, Tsalenko A, Deng DX, Connolly A, Zhang P, Yang E, Watt C, Yakhini Z, Ben-Dor A, Adler A, Bruhn L, Tsao P, Quertermous T, Ashley EA. King JY, et al. Among authors: connolly a. Physiol Genomics. 2005 Sep 21;23(1):103-18. doi: 10.1152/physiolgenomics.00101.2005. Epub 2005 Jun 7. Physiol Genomics. 2005. PMID: 15942018 Free article.
BRD4 (Bromodomain-Containing Protein 4) Interacts with GATA4 (GATA Binding Protein 4) to Govern Mitochondrial Homeostasis in Adult Cardiomyocytes.
Padmanabhan A, Alexanian M, Linares-Saldana R, González-Terán B, Andreoletti G, Huang Y, Connolly AJ, Kim W, Hsu A, Duan Q, Winchester SAB, Felix F, Perez-Bermejo JA, Wang Q, Li L, Shah PP, Haldar SM, Jain R, Srivastava D. Padmanabhan A, et al. Among authors: connolly aj. Circulation. 2020 Dec 15;142(24):2338-2355. doi: 10.1161/CIRCULATIONAHA.120.047753. Epub 2020 Oct 23. Circulation. 2020. PMID: 33094644 Free PMC article.
CD47-blocking antibodies restore phagocytosis and prevent atherosclerosis.
Kojima Y, Volkmer JP, McKenna K, Civelek M, Lusis AJ, Miller CL, Direnzo D, Nanda V, Ye J, Connolly AJ, Schadt EE, Quertermous T, Betancur P, Maegdefessel L, Matic LP, Hedin U, Weissman IL, Leeper NJ. Kojima Y, et al. Nature. 2016 Aug 4;536(7614):86-90. doi: 10.1038/nature18935. Epub 2016 Jul 20. Nature. 2016. PMID: 27437576 Free PMC article.
In vivo genetic profiling and cellular localization of apelin reveals a hypoxia-sensitive, endothelial-centered pathway activated in ischemic heart failure.
Sheikh AY, Chun HJ, Glassford AJ, Kundu RK, Kutschka I, Ardigo D, Hendry SL, Wagner RA, Chen MM, Ali ZA, Yue P, Huynh DT, Connolly AJ, Pelletier MP, Tsao PS, Robbins RC, Quertermous T. Sheikh AY, et al. Among authors: connolly aj. Am J Physiol Heart Circ Physiol. 2008 Jan;294(1):H88-98. doi: 10.1152/ajpheart.00935.2007. Epub 2007 Sep 28. Am J Physiol Heart Circ Physiol. 2008. PMID: 17906101 Free PMC article.
764 results