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A novel potent autophagy inhibitor ECDD-S27 targets vacuolar ATPase and inhibits cancer cell survival.
Paha J, Kanjanasirirat P, Munyoo B, Tuchinda P, Suvannang N, Nantasenamat C, Boonyarattanakalin K, Kittakoop P, Srikor S, Kongklad G, Rangkasenee N, Hongeng S, Utaisincharoen P, Borwornpinyo S, Ponpuak M. Paha J, et al. Among authors: kittakoop p. Sci Rep. 2019 Jun 24;9(1):9177. doi: 10.1038/s41598-019-45641-x. Sci Rep. 2019. PMID: 31235856 Free PMC article.
The amide derivative of anticopalic acid induces non-apoptotic cell death in triple-negative breast cancer cells by inhibiting FAK activation.
Chawengrum P, Luepongpatthana N, Thongnest S, Sirirak J, Boonsombat J, Lirdprapamongkol K, Keeratichamroen S, Kongwaen P, Montatip P, Kittakoop P, Svasti J, Ruchirawat S. Chawengrum P, et al. Among authors: kittakoop p. Sci Rep. 2023 Aug 18;13(1):13456. doi: 10.1038/s41598-023-40669-6. Sci Rep. 2023. PMID: 37596365 Free PMC article.
Depsidones inhibit aromatase activity and tumor cell proliferation in a co-culture of human primary breast adipose fibroblasts and T47D breast tumor cells.
Chottanapund S, Van Duursen MBM, Zwartsen A, Timtavorn S, Navasumrit P, Kittakoop P, Sureram S, Ruchirawat M, Van den Berg M. Chottanapund S, et al. Among authors: kittakoop p. Toxicol Rep. 2017 Mar 19;4:165-171. doi: 10.1016/j.toxrep.2017.03.004. eCollection 2017. Toxicol Rep. 2017. PMID: 28959637 Free PMC article.
A new 22,26-seco physalin steroid from Physalis angulata.
Boonsombat J, Chawengrum P, Mahidol C, Kittakoop P, Ruchirawat S, Thongnest S. Boonsombat J, et al. Among authors: kittakoop p. Nat Prod Res. 2020 Apr;34(8):1097-1104. doi: 10.1080/14786419.2018.1550766. Epub 2019 Jan 8. Nat Prod Res. 2020. PMID: 30616378
Vernodalidimer L, a sesquiterpene lactone dimer from Vernonia extensa and anti-tumor effects of vernodalin, vernolepin, and vernolide on HepG2 liver cancer cells.
Thongnest S, Chawengrum P, Keeratichamroen S, Lirdprapamongkol K, Eurtivong C, Boonsombat J, Kittakoop P, Svasti J, Ruchirawat S. Thongnest S, et al. Among authors: kittakoop p. Bioorg Chem. 2019 Nov;92:103197. doi: 10.1016/j.bioorg.2019.103197. Epub 2019 Aug 16. Bioorg Chem. 2019. PMID: 31445193
Discovery of New and Potent InhA Inhibitors as Antituberculosis Agents: Structure-Based Virtual Screening Validated by Biological Assays and X-ray Crystallography.
Kamsri P, Hanwarinroj C, Phusi N, Pornprom T, Chayajarus K, Punkvang A, Suttipanta N, Srimanote P, Suttisintong K, Songsiriritthigul C, Saparpakorn P, Hannongbua S, Rattanabunyong S, Seetaha S, Choowongkomon K, Sureram S, Kittakoop P, Hongmanee P, Santanirand P, Chen Z, Zhu W, Blood RA, Takebayashi Y, Hinchliffe P, Mulholland AJ, Spencer J, Pungpo P. Kamsri P, et al. Among authors: kittakoop p. J Chem Inf Model. 2020 Jan 27;60(1):226-234. doi: 10.1021/acs.jcim.9b00918. Epub 2019 Dec 27. J Chem Inf Model. 2020. PMID: 31820972
Identification of Potent DNA Gyrase Inhibitors Active against Mycobacterium tuberculosis.
Pakamwong B, Thongdee P, Kamsri B, Phusi N, Kamsri P, Punkvang A, Ketrat S, Saparpakorn P, Hannongbua S, Ariyachaokun K, Suttisintong K, Sureram S, Kittakoop P, Hongmanee P, Santanirand P, Spencer J, Mulholland AJ, Pungpo P. Pakamwong B, et al. Among authors: kittakoop p. J Chem Inf Model. 2022 Apr 11;62(7):1680-1690. doi: 10.1021/acs.jcim.1c01390. Epub 2022 Mar 29. J Chem Inf Model. 2022. PMID: 35347987
115 results