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Human pancreatic islet three-dimensional chromatin architecture provides insights into the genetics of type 2 diabetes.
Miguel-Escalada I, Bonàs-Guarch S, Cebola I, Ponsa-Cobas J, Mendieta-Esteban J, Atla G, Javierre BM, Rolando DMY, Farabella I, Morgan CC, García-Hurtado J, Beucher A, Morán I, Pasquali L, Ramos-Rodríguez M, Appel EVR, Linneberg A, Gjesing AP, Witte DR, Pedersen O, Grarup N, Ravassard P, Torrents D, Mercader JM, Piemonti L, Berney T, de Koning EJP, Kerr-Conte J, Pattou F, Fedko IO, Groop L, Prokopenko I, Hansen T, Marti-Renom MA, Fraser P, Ferrer J. Miguel-Escalada I, et al. Among authors: fraser p. Nat Genet. 2019 Jul;51(7):1137-1148. doi: 10.1038/s41588-019-0457-0. Epub 2019 Jun 28. Nat Genet. 2019. PMID: 31253982 Free PMC article.
Long-range chromatin regulatory interactions in vivo.
Carter D, Chakalova L, Osborne CS, Dai YF, Fraser P. Carter D, et al. Among authors: fraser p. Nat Genet. 2002 Dec;32(4):623-6. doi: 10.1038/ng1051. Epub 2002 Nov 11. Nat Genet. 2002. PMID: 12426570
The transcriptional interactome: gene expression in 3D.
Schoenfelder S, Clay I, Fraser P. Schoenfelder S, et al. Among authors: fraser p. Curr Opin Genet Dev. 2010 Apr;20(2):127-33. doi: 10.1016/j.gde.2010.02.002. Epub 2010 Mar 6. Curr Opin Genet Dev. 2010. PMID: 20211559 Review.
Single-cell Hi-C reveals cell-to-cell variability in chromosome structure.
Nagano T, Lubling Y, Stevens TJ, Schoenfelder S, Yaffe E, Dean W, Laue ED, Tanay A, Fraser P. Nagano T, et al. Among authors: fraser p. Nature. 2013 Oct 3;502(7469):59-64. doi: 10.1038/nature12593. Epub 2013 Sep 25. Nature. 2013. PMID: 24067610 Free PMC article.
Capture Hi-C identifies the chromatin interactome of colorectal cancer risk loci.
Jäger R, Migliorini G, Henrion M, Kandaswamy R, Speedy HE, Heindl A, Whiffin N, Carnicer MJ, Broome L, Dryden N, Nagano T, Schoenfelder S, Enge M, Yuan Y, Taipale J, Fraser P, Fletcher O, Houlston RS. Jäger R, et al. Among authors: fraser p. Nat Commun. 2015 Feb 19;6:6178. doi: 10.1038/ncomms7178. Nat Commun. 2015. PMID: 25695508 Free PMC article.
872 results