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Divergent Polypharmacology-Driven Cellular Activity of Structurally Similar Multi-Kinase Inhibitors through Cumulative Effects on Individual Targets.
Cell Chem Biol. 2019 Sep 19;26(9):1240-1252.e11. doi: 10.1016/j.chembiol.2019.06.003. Epub 2019 Jun 27.
Cell Chem Biol. 2019.
PMID: 31257184
Free PMC article.
Polypharmacology-based ceritinib repurposing using integrated functional proteomics.
Kuenzi BM, Remsing Rix LL, Stewart PA, Fang B, Kinose F, Bryant AT, Boyle TA, Koomen JM, Haura EB, Rix U.
Kuenzi BM, et al. Among authors: bryant at.
Nat Chem Biol. 2017 Dec;13(12):1222-1231. doi: 10.1038/nchembio.2489. Epub 2017 Oct 9.
Nat Chem Biol. 2017.
PMID: 28991240
Free PMC article.
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Dabrafenib inhibits the growth of BRAF-WT cancers through CDK16 and NEK9 inhibition.
Phadke M, Remsing Rix LL, Smalley I, Bryant AT, Luo Y, Lawrence HR, Schaible BJ, Chen YA, Rix U, Smalley KSM.
Phadke M, et al. Among authors: bryant at.
Mol Oncol. 2018 Jan;12(1):74-88. doi: 10.1002/1878-0261.12152. Epub 2017 Nov 23.
Mol Oncol. 2018.
PMID: 29112787
Free PMC article.
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IGF-binding proteins secreted by cancer-associated fibroblasts induce context-dependent drug sensitization of lung cancer cells.
Remsing Rix LL, Sumi NJ, Hu Q, Desai B, Bryant AT, Li X, Welsh EA, Fang B, Kinose F, Kuenzi BM, Chen YA, Antonia SJ, Lovly CM, Koomen JM, Haura EB, Marusyk A, Rix U.
Remsing Rix LL, et al. Among authors: bryant at.
Sci Signal. 2022 Aug 16;15(747):eabj5879. doi: 10.1126/scisignal.abj5879. Epub 2022 Aug 16.
Sci Signal. 2022.
PMID: 35973030
Free PMC article.
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The CLIP-170 N-terminal domain binds directly to both F-actin and microtubules in a mutually exclusive manner.
Wu YO, Miller RA, Alberico EO, Huang YAP, Bryant AT, Nelson NT, Jonasson EM, Goodson HV.
Wu YO, et al. Among authors: bryant at.
J Biol Chem. 2022 May;298(5):101820. doi: 10.1016/j.jbc.2022.101820. Epub 2022 Mar 10.
J Biol Chem. 2022.
PMID: 35283190
Free PMC article.
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Overexpression of the microtubule-binding protein CLIP-170 induces a +TIP network superstructure consistent with a biomolecular condensate.
Wu YO, Bryant AT, Nelson NT, Madey AG, Fernandes GF, Goodson HV.
Wu YO, et al. Among authors: bryant at.
PLoS One. 2021 Dec 10;16(12):e0260401. doi: 10.1371/journal.pone.0260401. eCollection 2021.
PLoS One. 2021.
PMID: 34890409
Free PMC article.
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Mental development of the South African native.
Bryant AT.
Bryant AT.
Eugen Rev. 1917 Apr;9(1):42-9.
Eugen Rev. 1917.
PMID: 21259633
Free PMC article.
No abstract available.
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