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Development of bisubstrate analog inhibitors of aspartate N-acetyltransferase, a critical brain enzyme.
Chem Biol Drug Des. 2020 Jan;95(1):48-57. doi: 10.1111/cbdd.13586. Epub 2019 Nov 20.
Chem Biol Drug Des. 2020.
PMID: 31260162
Design and optimization of aspartate N-acetyltransferase inhibitors for the potential treatment of Canavan disease.
Thangavelu B, Mutthamsetty V, Wang Q, Viola RE.
Thangavelu B, et al. Among authors: mutthamsetty v.
Bioorg Med Chem. 2017 Feb 1;25(3):870-885. doi: 10.1016/j.bmc.2016.11.060. Epub 2016 Dec 8.
Bioorg Med Chem. 2017.
PMID: 28007430
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