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The SPRINT trial suggests that markers of tubule cell function in the urine associate with risk of subsequent acute kidney injury while injury markers elevate after the injury.
Bullen AL, Katz R, Lee AK, Anderson CAM, Cheung AK, Garimella PS, Jotwani V, Haley WE, Ishani A, Lash JP, Neyra JA, Punzi H, Rastogi A, Riessen E, Malhotra R, Parikh CR, Rocco MV, Wall BM, Bhatt UY, Shlipak MG, Ix JH, Estrella MM. Bullen AL, et al. Among authors: malhotra r. Kidney Int. 2019 Aug;96(2):470-479. doi: 10.1016/j.kint.2019.03.024. Epub 2019 May 7. Kidney Int. 2019. PMID: 31262489 Free PMC article. Clinical Trial.
Association Between More Intensive vs Less Intensive Blood Pressure Lowering and Risk of Mortality in Chronic Kidney Disease Stages 3 to 5: A Systematic Review and Meta-analysis.
Malhotra R, Nguyen HA, Benavente O, Mete M, Howard BV, Mant J, Odden MC, Peralta CA, Cheung AK, Nadkarni GN, Coleman RL, Holman RR, Zanchetti A, Peters R, Beckett N, Staessen JA, Ix JH. Malhotra R, et al. JAMA Intern Med. 2017 Oct 1;177(10):1498-1505. doi: 10.1001/jamainternmed.2017.4377. JAMA Intern Med. 2017. PMID: 28873137 Free PMC article. Review.
The Effect of Extended Release Niacin on Markers of Mineral Metabolism in CKD.
Malhotra R, Katz R, Hoofnagle A, Bostom A, Rifkin DE, Mcbride R, Probstfield J, Block G, Ix JH. Malhotra R, et al. Clin J Am Soc Nephrol. 2018 Jan 6;13(1):36-44. doi: 10.2215/CJN.05440517. Epub 2017 Dec 5. Clin J Am Soc Nephrol. 2018. PMID: 29208626 Free PMC article. Clinical Trial.
Urinary Biomarkers of Tubular Damage Are Associated with Mortality but Not Cardiovascular Risk among Systolic Blood Pressure Intervention Trial Participants with Chronic Kidney Disease.
Jotwani VK, Lee AK, Estrella MM, Katz R, Garimella PS, Malhotra R, Rifkin DE, Ambrosius W, Freedman BI, Cheung AK, Raphael KL, Drawz P, Neyra JA, Oparil S, Punzi H, Shlipak MG, Ix JH; for the SPRINT Research Group. Jotwani VK, et al. Among authors: malhotra r. Am J Nephrol. 2019;49(5):346-355. doi: 10.1159/000499531. Epub 2019 Apr 2. Am J Nephrol. 2019. PMID: 30939472 Free PMC article. Clinical Trial.
1,860 results