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Colon cancer-derived oncogenic EGFR G724S mutant identified by whole genome sequence analysis is dependent on asymmetric dimerization and sensitive to cetuximab.
Cho J, Bass AJ, Lawrence MS, Cibulskis K, Cho A, Lee SN, Yamauchi M, Wagle N, Pochanard P, Kim N, Park AK, Won J, Hur HS, Greulich H, Ogino S, Sougnez C, Voet D, Tabernero J, Jimenez J, Baselga J, Gabriel SB, Lander ES, Getz G, Eck MJ, Park WY, Meyerson M. Cho J, et al. Among authors: kim n. Mol Cancer. 2014 Jun 4;13:141. doi: 10.1186/1476-4598-13-141. Mol Cancer. 2014. PMID: 24894453 Free PMC article.
Structure and mechanism of activity-based inhibition of the EGF receptor by Mig6.
Park E, Kim N, Ficarro SB, Zhang Y, Lee BI, Cho A, Kim K, Park AKJ, Park WY, Murray B, Meyerson M, Beroukhim R, Marto JA, Cho J, Eck MJ. Park E, et al. Among authors: kim n, kim k. Nat Struct Mol Biol. 2015 Sep;22(9):703-711. doi: 10.1038/nsmb.3074. Epub 2015 Aug 17. Nat Struct Mol Biol. 2015. PMID: 26280531 Free PMC article.
Integrated genomic approaches identify upregulation of SCRN1 as a novel mechanism associated with acquired resistance to erlotinib in PC9 cells harboring oncogenic EGFR mutation.
Kim N, Cho A, Watanabe H, Choi YL, Aziz M, Kassner M, Joung JG, Park AK, Francis JM, Bae JS, Ahn SM, Kim KM, Park JO, Park WY, Ahn MJ, Park K, Koo J, Yin HH, Cho J. Kim N, et al. Among authors: kim km. Oncotarget. 2016 Mar 22;7(12):13797-809. doi: 10.18632/oncotarget.7318. Oncotarget. 2016. PMID: 26883194 Free PMC article.
Loss of desmoglein-2 promotes gallbladder carcinoma progression and resistance to EGFR-targeted therapy through Src kinase activation.
Lee SH, Kim JM, Lee DG, Lee J, Park JG, Han TS, Cho HS, Cho YL, Bae KH, Park YJ, Lee SJ, Lee MS, Huh YM, Jo DY, Yun HJ, Jeon HJ, Kim N, Joo M, Kim JS, Lee HJ, Min JK. Lee SH, et al. Among authors: kim jm, kim n, kim js. Cell Death Differ. 2021 Mar;28(3):968-984. doi: 10.1038/s41418-020-00628-4. Epub 2020 Sep 28. Cell Death Differ. 2021. PMID: 32989241 Free PMC article.
Body mass index as a predictor of advanced colorectal neoplasia.
Kwon HJ, Kim HJ, Park YS, Lim JH, Park KJ, Shin CM, Hwang JH, Kim JW, Jeong SH, Kim N, Lee DH. Kwon HJ, et al. Among authors: kim hj, kim n, kim jw. J Cancer Prev. 2013 Jun;18(2):144-8. doi: 10.15430/jcp.2013.18.2.144. J Cancer Prev. 2013. PMID: 25337540 Free PMC article.
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