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Coordinate loss of MAP3K7 and CHD1 promotes aggressive prostate cancer.
Rodrigues LU, Rider L, Nieto C, Romero L, Karimpour-Fard A, Loda M, Lucia MS, Wu M, Shi L, Cimic A, Sirintrapun SJ, Nolley R, Pac C, Chen H, Peehl DM, Xu J, Liu W, Costello JC, Cramer SD. Rodrigues LU, et al. Cancer Res. 2015 Mar 15;75(6):1021-34. doi: 10.1158/0008-5472.CAN-14-1596. Cancer Res. 2015. PMID: 25770290 Free PMC article.
MAP3K7 Loss Drives Enhanced Androgen Signaling and Independently Confers Risk of Recurrence in Prostate Cancer with Joint Loss of CHD1.
Jillson LK, Rider LC, Rodrigues LU, Romero L, Karimpour-Fard A, Nieto C, Gillette C, Torkko K, Danis E, Smith EE, Nolley R, Peehl DM, Lucia MS, Costello JC, Cramer SD. Jillson LK, et al. Among authors: rider lc. Mol Cancer Res. 2021 Jul;19(7):1123-1136. doi: 10.1158/1541-7786.MCR-20-0913. Epub 2021 Apr 12. Mol Cancer Res. 2021. PMID: 33846123 Free PMC article.
Lipid catabolism via CPT1 as a therapeutic target for prostate cancer.
Schlaepfer IR, Rider L, Rodrigues LU, Gijón MA, Pac CT, Romero L, Cimic A, Sirintrapun SJ, Glodé LM, Eckel RH, Cramer SD. Schlaepfer IR, et al. Mol Cancer Ther. 2014 Oct;13(10):2361-71. doi: 10.1158/1535-7163.MCT-14-0183. Epub 2014 Aug 13. Mol Cancer Ther. 2014. PMID: 25122071 Free PMC article.
SPOP the mutation.
Rider L, Cramer SD. Rider L, et al. Elife. 2015 Oct 27;4:e11760. doi: 10.7554/eLife.11760. Elife. 2015. PMID: 26506153 Free PMC article.