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NMR-Based Activity Assays for Determining Compound Inhibition, IC50 Values, Artifactual Activity, and Whole-Cell Activity of Nucleoside Ribohydrolases.
Stockman BJ, Kaur A, Persaud JK, Mahmood M, Thuilot SF, Emilcar MB, Canestrari M, Gonzalez JA, Auletta S, Sapojnikov V, Caravan W, Muellers SN. Stockman BJ, et al. Among authors: muellers sn. J Vis Exp. 2019 Jun 30;(148):10.3791/59928. doi: 10.3791/59928. J Vis Exp. 2019. PMID: 31305530 Free PMC article.
Interaction Energetics and Druggability of the Protein-Protein Interaction between Kelch-like ECH-Associated Protein 1 (KEAP1) and Nuclear Factor Erythroid 2 Like 2 (Nrf2).
Zhong M, Lynch A, Muellers SN, Jehle S, Luo L, Hall DR, Iwase R, Carolan JP, Egbert M, Wakefield A, Streu K, Harvey CM, Ortet PC, Kozakov D, Vajda S, Allen KN, Whitty A. Zhong M, et al. Among authors: muellers sn. Biochemistry. 2020 Feb 4;59(4):563-581. doi: 10.1021/acs.biochem.9b00943. Epub 2020 Jan 2. Biochemistry. 2020. PMID: 31851823 Free PMC article.