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Neuronal vulnerability and multilineage diversity in multiple sclerosis.
Schirmer L, Velmeshev D, Holmqvist S, Kaufmann M, Werneburg S, Jung D, Vistnes S, Stockley JH, Young A, Steindel M, Tung B, Goyal N, Bhaduri A, Mayer S, Engler JB, Bayraktar OA, Franklin RJM, Haeussler M, Reynolds R, Schafer DP, Friese MA, Shiow LR, Kriegstein AR, Rowitch DH. Schirmer L, et al. Among authors: young a. Nature. 2019 Sep;573(7772):75-82. doi: 10.1038/s41586-019-1404-z. Epub 2019 Jul 17. Nature. 2019. PMID: 31316211 Free PMC article.
Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes.
Hammond TR, Dufort C, Dissing-Olesen L, Giera S, Young A, Wysoker A, Walker AJ, Gergits F, Segel M, Nemesh J, Marsh SE, Saunders A, Macosko E, Ginhoux F, Chen J, Franklin RJM, Piao X, McCarroll SA, Stevens B. Hammond TR, et al. Among authors: young a. Immunity. 2019 Jan 15;50(1):253-271.e6. doi: 10.1016/j.immuni.2018.11.004. Epub 2018 Nov 21. Immunity. 2019. PMID: 30471926 Free PMC article.
Niche stiffness underlies the ageing of central nervous system progenitor cells.
Segel M, Neumann B, Hill MFE, Weber IP, Viscomi C, Zhao C, Young A, Agley CC, Thompson AJ, Gonzalez GA, Sharma A, Holmqvist S, Rowitch DH, Franze K, Franklin RJM, Chalut KJ. Segel M, et al. Among authors: young a. Nature. 2019 Sep;573(7772):130-134. doi: 10.1038/s41586-019-1484-9. Epub 2019 Aug 15. Nature. 2019. PMID: 31413369 Free PMC article.
Ageing causes a decline in tissue regeneration owing to a loss of function of adult stem cell and progenitor cell populations(1). One example is the deterioration of the regenerative capacity of the widespread and abundant population of central nervous system (CNS) …
Ageing causes a decline in tissue regeneration owing to a loss of function of adult stem cell and progenitor cell populations( …
Myc determines the functional age state of oligodendrocyte progenitor cells.
Neumann B, Segel M, Ghosh T, Zhao C, Tourlomousis P, Young A, Förster S, Sharma A, Chen CZ, Cubillos JF, Rawji KS, Chalut KJ, Franklin RJM. Neumann B, et al. Among authors: young a. Nat Aging. 2021 Sep;1(9):826-837. doi: 10.1038/s43587-021-00109-4. Epub 2021 Sep 14. Nat Aging. 2021. PMID: 37117631
7,568 results