Galectin-1 interacts with the human endogenous retroviral envelope protein syncytin-2 and potentiates trophoblast fusion in humans.
Toudic C, Vargas A, Xiao Y, St-Pierre G, Bannert N, Lafond J, Rassart É, Sato S, Barbeau B.
Toudic C, et al. Among authors: vargas a.
FASEB J. 2019 Nov;33(11):12873-12887. doi: 10.1096/fj.201900107R. Epub 2019 Sep 7.
FASEB J. 2019.
PMID: 31499012
Free PMC article.
Infection assays showed a specific and significant effect of Gal-1 on the infectivity of Syn-2-pseudotyped viruses that depended on the expression of major facilitator superfamily domain-containing 2A (MFSD2a). ...We conclude that Gal-1 specifically interacts with Syn-2 an …
Infection assays showed a specific and significant effect of Gal-1 on the infectivity of Syn-2-pseudotyped viruses that depended on t …